Human ErbB3/Her3 PE-conjugated Antibody | R&D Systems FAB3481P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human ErbB3/Her3 PE-conjugated Antibody

catalog :

FAB3481P

quantity :

25 Tests

price :

159 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

66223

reactivity :

human

application :

flow cytometry

citations: 8

Reference
De Pauw I, Lardon F, Van den Bossche J, Baysal H, Fransen E, Deschoolmeester V, et al. Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines. Mol Oncol. 2018;12:830-854 pubmed publisher
Keri S, Szabo C, Kelemen O. Uniting the neurodevelopmental and immunological hypotheses: Neuregulin 1 receptor ErbB and Toll-like receptor activation in first-episode schizophrenia. Sci Rep. 2017;7:4147 pubmed publisher
Cheng H, Terai M, Kageyama K, Ozaki S, McCue P, Sato T, et al. Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma. Cancer Res. 2015;75:2737-48 pubmed publisher
Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, et al. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE. 2014;9:e84417 pubmed publisher
Mimura K, Shiraishi K, Mueller A, Izawa S, Kua L, So J, et al. The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer. J Immunol. 2013;191:6261-72 pubmed publisher
Macleod S, Elgadi M, Bossi G, Sankar U, Pisio A, Agopsowicz K, et al. HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice. Cancer Gene Ther. 2012;19:888-98 pubmed publisher
Zhang Y, Gonzalez R, Zangar R. Protein secretion in human mammary epithelial cells following HER1 receptor activation: influence of HER2 and HER3 expression. BMC Cancer. 2011;11:69 pubmed publisher
Richards K, Zweidler McKay P, Van Roy N, Speleman F, Trevino J, Zage P, et al. Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo. Cancer. 2010;116:3233-43 pubmed publisher

product information

brand :

R&D Systems

master code :

FAB3481P

SKU :

FAB3481P-025

product name :

Human ErbB3/Her3 PE-conjugated Antibody

description :

The Human ErbB3/Her3 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to ErbB3/Her3. This antibody reacts with human. The Human ErbB3/Her3 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

ErbB3/Her3

category :

Primary Antibodies

unit size :

25 Tests

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

66223

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human ErbB3/Her3, Ser20-Thr643, Accession # P21860

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human ErbB3/Her3 in direct ELISAs. Does not cross-react with recombinant human EGF R.

gene symbol :

ERBB3

catalog number base :

FAB3481P

accessionNumbers :

P21860

applications :

Flow Cytometry

2020 USD :

159

2021 USD :

159 USD

alt names :

c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.