product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ErbB3/Her3 PE-conjugated Antibody
catalog :
FAB3481P-100
quantity :
100 Tests (also 25 Tests)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
66223
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Reference
de Kay J, Carver J, Shevenell B, Kosta A, Tsibulnikov S, Certo E, et al. Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus. Cell Signal. 2022;96:110360 pubmed publisher
De Pauw I, Lardon F, Van den Bossche J, Baysal H, Fransen E, Deschoolmeester V, et al. Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines. Mol Oncol. 2018;12:830-854 pubmed publisher
Keri S, Szabo C, Kelemen O. Uniting the neurodevelopmental and immunological hypotheses: Neuregulin 1 receptor ErbB and Toll-like receptor activation in first-episode schizophrenia. Sci Rep. 2017;7:4147 pubmed publisher
Ryzhov S, Matafonov A, Galindo C, Zhang Q, Tran T, Lenihan D, et al. ERBB signaling attenuates proinflammatory activation of nonclassical monocytes. Am J Physiol Heart Circ Physiol. 2017;312:H907-H918 pubmed publisher
Wandinger S, Lahortiga I, Jacobs K, Klammer M, Jordan N, Elschenbroich S, et al. Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling. PLoS ONE. 2016;11:e0146100 pubmed publisher
Cheng H, Terai M, Kageyama K, Ozaki S, McCue P, Sato T, et al. Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma. Cancer Res. 2015;75:2737-48 pubmed publisher
Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, et al. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. PLoS ONE. 2014;9:e84417 pubmed publisher
Mimura K, Shiraishi K, Mueller A, Izawa S, Kua L, So J, et al. The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer. J Immunol. 2013;191:6261-72 pubmed publisher
Macleod S, Elgadi M, Bossi G, Sankar U, Pisio A, Agopsowicz K, et al. HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice. Cancer Gene Ther. 2012;19:888-98 pubmed publisher
Zhang Y, Gonzalez R, Zangar R. Protein secretion in human mammary epithelial cells following HER1 receptor activation: influence of HER2 and HER3 expression. BMC Cancer. 2011;11:69 pubmed publisher
Richards K, Zweidler McKay P, Van Roy N, Speleman F, Trevino J, Zage P, et al. Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo. Cancer. 2010;116:3233-43 pubmed publisher
product information
master code :
FAB3481P
SKU :
FAB3481P-100
product name :
Human ErbB3/Her3 PE-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human ErbB3/Her3 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to ErbB3/Her3. This antibody reacts with human. The Human ErbB3/Her3 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Cell Selection.
target :
ErbB3/Her3
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
66223
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ErbB3/Her3, Ser20-Thr643, Accession # P21860
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human ErbB3/Her3 in direct ELISAs. Does not cross-react with recombinant human EGF R.
gene symbol :
ERBB3
top caption :
Detection of ErbB3/Her3 antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P21860
applications :
Flow Cytometry,Cell Selection
USD :
429 USD
alt names :
c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.