product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ErbB3/Her3 APC-conjugated Antibody
catalog :
FAB3481A-100
quantity :
100 Tests (also 25 Tests)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
66223
reactivity :
human
application :
flow cytometry
more info or order :
citations: 4
Reference
Tamura S, Wang Y, Veeneman B, Hovelson D, Bankhead A, Broses L, et al. Molecular Correlates of In Vitro Responses to Dacomitinib and Afatinib in Bladder Cancer. Bladder Cancer. 2018;4:77-90 pubmed publisher
Marlowe T, Lenzo F, Figel S, Grapes A, Cance W. Oncogenic Receptor Tyrosine Kinases Directly Phosphorylate Focal Adhesion Kinase (FAK) as a Resistance Mechanism to FAK-Kinase Inhibitors. Mol Cancer Ther. 2016;15:3028-3039 pubmed
Stindt S, Cebula P, Albrecht U, Keitel V, Schulte Am Esch J, Knoefel W, et al. Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family. PLoS ONE. 2016;11:e0148711 pubmed publisher
Sie M, den Dunnen W, Lourens H, Meeuwsen de Boer T, Scherpen F, Zomerman W, et al. Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma. PLoS ONE. 2015;10:e0122555 pubmed publisher
product information
master code :
FAB3481A
SKU :
FAB3481A-100
product name :
Human ErbB3/Her3 APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human ErbB3/Her3 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to ErbB3/Her3. This antibody reacts with human. The Human ErbB3/Her3 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
ErbB3/Her3
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
66223
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ErbB3/Her3, Ser20-Thr643, Accession # P21860
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human ErbB3/Her3 in ELISAs. In sandwich immunoassays, no cross-reactivity with recombinant human EGF R is observed.
gene symbol :
ERBB3
top caption :
Detection of ErbB3/Her3 antibody in MCF-7 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P21860
applications :
Flow Cytometry
USD :
469 USD
alt names :
c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.