Human CXCR2/IL-8RB Fluorescein-conjugated Antibody | R&D Systems FAB331F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCR2/IL-8RB Fluorescein-conjugated Antibody

catalog :

FAB331F

quantity :

25 Tests (also 100 Tests)

price :

99 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

48311

reactivity :

human

application :

flow cytometry

citations: 7

Reference
Hazeldine J, Harris P, Chapple I, Grant M, Greenwood H, Livesey A, et al. Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. Aging Cell. 2014;13:690-8 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Liu L, Xie F, Chang K, Li M, Meng Y, Wang X, et al. Hypoxia promotes the proliferation of cervical carcinoma cells through stimulating the secretion of IL-8. Int J Clin Exp Pathol. 2014;7:575-83 pubmed
Eikawa S, Ohue Y, Kitaoka K, Aji T, Uenaka A, Oka M, et al. Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6. J Immunol. 2010;185:6734-40 pubmed publisher
Yang G, Rosen D, Liu G, Yang F, Guo X, Xiao X, et al. CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin Cancer Res. 2010;16:3875-86 pubmed publisher
Maxwell P, Gallagher R, Seaton A, Wilson C, Scullin P, Pettigrew J, et al. HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene. 2007;26:7333-45 pubmed
Mihara K, Smit M, Krajnc Franken M, Gossen J, Rooseboom M, Dokter W. Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice. Eur J Immunol. 2005;35:2573-82 pubmed

product information

brand :

R&D Systems

master code :

FAB331F

SKU :

FAB331F-025

product name :

Human CXCR2/IL-8RB Fluorescein-conjugated Antibody

description :

The Human CXCR2/IL-8RB Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CXCR2/IL-8RB. This antibody reacts with human. The Human CXCR2/IL-8RB Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

CXCR2/IL-8RB

category :

Primary Antibodies

unit size :

25 Tests (also 100 Tests)

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

48311

conjugate :

Fluorescein

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CXCR2/IL-8 RB, Met1-Leu355, Accession # AAB25880

isotype :

IgG2a

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).

gene symbol :

CXCR2

catalog number base :

FAB331F

accessionNumbers :

AAB25880

applications :

Flow Cytometry

extended description :

Clone 48311 was used by HLDA to establish CD designation

2020 USD :

2021 USD :

99 USD

product details :

Clone 48311 was used by HLDA to establish CD designation

alt names :

CD182, CD182 antigen, CDw128b, chemokine (C-X-C motif) receptor 2, chemokine (CXC) receptor 2, CMKAR2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CXCR2 gene for IL8 receptor type B, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8 RB, IL-8 receptor type 2, IL-8R B, IL8R2, IL8RA, IL8RB, interleukin 8 receptor B, interleukin 8 receptor type 2, interleukin-8 receptor type B

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.