Human CXCR2/IL-8RB Fluorescein-conjugated Antibody | R&D Systems FAB331F-025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCR2/IL-8RB Fluorescein-conjugated Antibody

catalog :

FAB331F-025

quantity :

25 Tests (also 100 Tests)

price :

129 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

48311

reactivity :

human, mouse

application :

immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Ignacio R, Dong Y, Kabir S, Choi H, Lee E, Wilson A, et al. CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer. Oncotarget. 2018;9:9751-9765 pubmed publisher
Hazeldine J, Harris P, Chapple I, Grant M, Greenwood H, Livesey A, et al. Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. Aging Cell. 2014;13:690-8 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Liu L, Xie F, Chang K, Li M, Meng Y, Wang X, et al. Hypoxia promotes the proliferation of cervical carcinoma cells through stimulating the secretion of IL-8. Int J Clin Exp Pathol. 2014;7:575-83 pubmed
Eikawa S, Ohue Y, Kitaoka K, Aji T, Uenaka A, Oka M, et al. Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6. J Immunol. 2010;185:6734-40 pubmed publisher
Yang G, Rosen D, Liu G, Yang F, Guo X, Xiao X, et al. CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin Cancer Res. 2010;16:3875-86 pubmed publisher
Maxwell P, Gallagher R, Seaton A, Wilson C, Scullin P, Pettigrew J, et al. HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene. 2007;26:7333-45 pubmed
Mihara K, Smit M, Krajnc Franken M, Gossen J, Rooseboom M, Dokter W. Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice. Eur J Immunol. 2005;35:2573-82 pubmed
Frendeus B, Godaly G, Hang L, Karpman D, Lundstedt A, Svanborg C. Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart. J Exp Med. 2000;192:881-90 pubmed

product information

brand :

R&D Systems

master code :

FAB331F

SKU :

FAB331F-025

product name :

Human CXCR2/IL-8RB Fluorescein-conjugated Antibody

unit size :

25 Tests (also 100 Tests)

seo description :

The Human CXCR2/IL-8RB Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CXCR2/IL-8RB. This antibody reacts with human,mouse. The Human CXCR2/IL-8RB Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry.

target :

CXCR2/IL-8RB

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

48311

conjugate :

Fluorescein

dilution :

Flow Cytometry 10 uL/10^6 cells

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CXCR2/IL-8 RB, Met1-Leu355, Accession # AAB25880

isotype :

IgG2a

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).

gene symbol :

CXCR2

top caption :

Detection of CXCR2/IL-8 RB antibody in Human Peripheral Blood Granulocytes antibody by Flow Cytometry.

accessionNumbers :

AAB25880

applications :

Flow Cytometry,Immunocytochemistry

extended description :

Clone 48311 was used by HLDA to establish CD designation

USD :

129 USD

product details :

Clone 48311 was used by HLDA to establish CD designation

alt names :

CD182, CD182 antigen, CDw128b, chemokine (C-X-C motif) receptor 2, chemokine (CXC) receptor 2, CMKAR2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CXCR2 gene for IL8 receptor type B, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8 RB, IL-8 receptor type 2, IL-8R B, IL8R2, IL8RA, IL8RB, interleukin 8 receptor B, interleukin 8 receptor type 2, interleukin-8 receptor type B

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage