product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Mesothelin APC-conjugated Antibody
catalog :
FAB32652A
quantity :
100 Tests
price :
509 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
420411
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Lee D, Dunn Z, Guo W, Rosenthal C, Penn N, Yu Y, et al. Unlocking the potential of allogeneic Vδ2 T cells for ovarian cancer therapy through CD16 biomarker selection and CAR/IL-15 engineering. Nat Commun. 2023;14:6942 pubmed publisher
Sommerfeld L, Knuth I, Finkernagel F, Pesek J, Nockher W, Jansen J, et al. Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment. Cancers (Basel). 2022;14: pubmed publisher
Schoutrop E, Renken S, Micallef Nilsson I, Hahn P, Poiret T, Kiessling R, et al. Trogocytosis and fratricide killing impede MSLN-directed CAR T cell functionality. Oncoimmunology. 2022;11:2093426 pubmed publisher
Ye L, Lou Y, Lu L, Fan X. Mesothelin-targeted second generation CAR-T cells inhibit growth of mesothelin-expressing tumors in vivo. Exp Ther Med. 2019;17:739-747 pubmed publisher
Servais E, Suzuki K, Colovos C, Rodriguez L, Sima C, Fleisher M, et al. An in vivo platform for tumor biomarker assessment. PLoS ONE. 2011;6:e26722 pubmed publisher
product information
master code :
FAB32652A
SKU :
FAB32652A
product name :
Human Mesothelin APC-conjugated Antibody
unit size :
100 Tests
description :
The Human Mesothelin APC-conjugated Antibody from R&D Systems is a rat monoclonal antibody to Mesothelin. This antibody reacts with human. The Human Mesothelin APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
Mesothelin
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
420411
conjugate :
Allophycocyanin
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Mesothelin, Glu296-Gly580, Accession # AAH09272
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Mesothelin in direct ELISAs.
gene symbol :
MSLN
top caption :
Detection of Mesothelin antibody in HeLa Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
AAH09272
applications :
Flow Cytometry
USD :
509 USD
alt names :
CAK1, CAK1 antigen, megakaryocyte potentiating factor, mesothelin, MPF, MPFSMRP, MSLN, Pre-pro-megakaryocyte-potentiating factor, SMR, soluble MPF mesothelin related protein
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.