product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human VEGFR1/Flt-1 PE-conjugated Antibody
catalog :
FAB321P
quantity :
100 Tests
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
49560
reactivity :
human
application :
flow cytometry
more info or order :
citations: 22
Reference
Oudard S, Benhamouda N, Escudier B, Ravel P, Tran T, Levionnois E, et al. Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma. Cells. 2021;11: pubmed publisher
Bergamo M, Zhang Z, Oliveira T, N xf6 r J. VEGFR1 primes a unique cohort of dental pulp stem cells for vasculogenic differentiation. Eur Cell Mater. 2021;41:332-344 pubmed publisher
Witkowska M, Majchrzak A, Cebula Obrzut B, Wawrzyniak E, Robak T, Smolewski P. The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia. Tumour Biol. 2017;39:1010428317694551 pubmed publisher
Guo P, Yang J, Bielenberg D, Dillon D, Zurakowski D, Moses M, et al. A quantitative method for screening and identifying molecular targets for nanomedicine. J Control Release. 2017;263:57-67 pubmed publisher
Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez Coral A, et al. BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth. Clin Cancer Res. 2015;21:1652-64 pubmed publisher
Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, et al. Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. BMC Cancer. 2014;14:939 pubmed publisher
Norton K, Han Z, Popel A, Pandey N. Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells. Onco Targets Ther. 2014;7:1571-82 pubmed publisher
Mesti T, Savarin P, Triba M, Le Moyec L, Ocvirk J, Banissi C, et al. Metabolic impact of anti-angiogenic agents on U87 glioma cells. PLoS ONE. 2014;9:e99198 pubmed publisher
Stamati K, Priestley J, Mudera V, Cheema U. Laminin promotes vascular network formation in 3D in vitro collagen scaffolds by regulating VEGF uptake. Exp Cell Res. 2014;327:68-77 pubmed publisher
Park S, Kim K, Kim W, Cho C. Interaction of mesenchymal stem cells with fibroblast-like synoviocytes via cadherin-11 promotes angiogenesis by enhanced secretion of placental growth factor. J Immunol. 2014;192:3003-10 pubmed publisher
Shantsila E, Wrigley B, Tapp L, Apostolakis S, Montoro Garcia S, Drayson M, et al. Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. J Thromb Haemost. 2011;9:1056-66 pubmed publisher
Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood. 2010;116:3099-107 pubmed publisher
Nilsson M, Zage P, Zeng L, Xu L, Cascone T, Wu H, et al. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors. Oncogene. 2010;29:2938-49 pubmed publisher
Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, et al. Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property. J Immunol. 2009;183:8176-85 pubmed publisher
Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, et al. VEGFR2 is selectively expressed by FOXP3high CD4+ Treg. Eur J Immunol. 2010;40:197-203 pubmed publisher
Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, et al. Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells. J Cell Physiol. 2008;217:261-80 pubmed publisher
Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, et al. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Exp Hematol. 2008;36:545-558 pubmed publisher
Narazaki M, Segarra M, Tosato G. Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A. Blood. 2008;111:4126-36 pubmed publisher
Shawber C, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell S, et al. Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest. 2007;117:3369-82 pubmed
Ball S, Shuttleworth C, Kielty C. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol. 2007;177:489-500 pubmed
Karrar A, Broome U, Uzunel M, Qureshi A, Sumitran Holgersson S. Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Gut. 2007;56:243-52 pubmed
Danet G, Pan Y, Luongo J, Bonnet D, Simon M. Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest. 2003;112:126-35 pubmed
product information
master code :
FAB321P
SKU :
FAB321P
product name :
Human VEGFR1/Flt-1 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human VEGFR1/Flt-1 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR1/Flt-1. This antibody reacts with human,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque). The Human VEGFR1/Flt-1 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
VEGFR1/Flt-1
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
49560
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF R1/Flt-1, Ser27-His687, Accession # NP_001153392
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
specificity :
Detects human VEGF R1/Flt-1 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse VEGF R1, recombinant human (rh) VEGF R2, rhVEGF R3, or rhVEGF R4.
gene symbol :
FLT1
top caption :
Detection of VEGF R1/Flt-1 antibody in HUVEC Human Cells antibody by Flow Cytometry.
accessionNumbers :
NP_001153392
applications :
Flow Cytometry
USD :
439 USD
alt names :
EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.