Human Tie-2 PE-conjugated Antibody | R&D Systems FAB3131P product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Tie-2 PE-conjugated Antibody

catalog :

FAB3131P

quantity :

100 Tests

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

83715

reactivity :

human, bovine

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 16

Reference
Molinos M, Fiordalisi M, Caldeira J, Almeida C, Barbosa M, Gon xe7 alves R. Alterations of bovine nucleus pulposus cells with aging. Aging Cell. 2023;22:e13873 pubmed publisher
Reijrink M, Van Ark J, Lexis C, Visser L, Lodewijk M, van der Horst I, et al. Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus. Cardiovasc Diabetol. 2022;21:72 pubmed publisher
Guerrero J, H xe4 ckel S, Croft A, Albers C, Gantenbein B. The effects of 3D culture on the expansion and maintenance of nucleus pulposus progenitor cell multipotency. JOR Spine. 2021;4:e1131 pubmed publisher
Han Q, Zhang Q, Ying F, Wang Z, Zhang Y, Gong L, et al. Circulating Tie2-Expressing Monocytes: A Potential Biomarker for Cervical Cancer. Onco Targets Ther. 2020;13:8877-8885 pubmed publisher
Triantafyllou E, Pop O, Possamai L, Wilhelm A, Liaskou E, Singanayagam A, et al. MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. Gut. 2018;67:333-347 pubmed publisher
Clark G, Kupresanin F, Fromm P, Ju X, Muusers L, Silveira P, et al. New insights into the phenotype of human dendritic cell populations. Clin Transl Immunology. 2016;5:e61 pubmed publisher
Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, et al. Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. BMC Cancer. 2014;14:939 pubmed publisher
Forgèt M, Voorhees J, Cole S, Dakhlallah D, Patterson I, Gross A, et al. Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. PLoS ONE. 2014;9:e98623 pubmed publisher
Gabrusiewicz K, Liu D, Cortes Santiago N, Hossain M, Conrad C, Aldape K, et al. Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes. Oncotarget. 2014;5:2208-20 pubmed
Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, et al. slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells. Nat Commun. 2014;5:3029 pubmed publisher
Pelosi E, Castelli G, Martin Padura I, Bordoni V, Santoro S, Conigliaro A, et al. Human haemato-endothelial precursors: cord blood CD34+ cells produce haemogenic endothelium. PLoS ONE. 2012;7:e51109 pubmed publisher
Schauer D, Starlinger P, Reiter C, Jahn N, Zajc P, Buchberger E, et al. Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer. PLoS ONE. 2012;7:e44450 pubmed publisher
Suga H, Eto H, Shigeura T, Inoue K, Aoi N, Kato H, et al. IFATS collection: Fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism. Stem Cells. 2009;27:238-49 pubmed publisher
Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, et al. Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells. J Cell Physiol. 2008;217:261-80 pubmed publisher
Cai J, Kehoe O, Smith G, Hykin P, Boulton M. The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy. Invest Ophthalmol Vis Sci. 2008;49:2163-71 pubmed publisher
Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, et al. Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages. Br J Haematol. 2006;135:703-14 pubmed

product information

master code :

FAB3131P

SKU :

FAB3131P

product name :

Human Tie-2 PE-conjugated Antibody

unit size :

100 Tests

description :

The Human Tie-2 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Tie-2. This antibody reacts with bovine,human,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque). The Human Tie-2 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

Tie-2

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

83715

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Tie-2, Ala23-Lys745, Accession # AAA61139

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Bovine,Human,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)

specificity :

Detects human Tie-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tie-1, recombinant mouse Tie-2, or recombinant zebrafish Tie-2 is observed.

gene symbol :

TEK

top caption :

Detection of Tie-2 antibody in HUVEC Human Cells antibody by Flow Cytometry.

accessionNumbers :

AAA61139

applications :

Flow Cytometry

USD :

399 USD

alt names :

angiopoietin-1 receptor, CD202B, CD202b antigen, EC 2.7.10, EC 2.7.10.1, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, TEK, TEK tyrosine kinase, endothelial, Tie2, TIE-2, TIE2CD202b, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, venous malformations, multiple cutaneous and mucosal, VMCM, VMCM1

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage