product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Tie-2 APC-conjugated Antibody
catalog :
FAB3131A
quantity :
100 Tests
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
83715
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 12
Reference
Otani Y, Schol J, Sakai D, Nakamura Y, Sako K, Warita T, et al. Assessment of Tie2-Rejuvenated Nucleus Pulposus Cell Transplants from Young and Old Patient Sources Demonstrates That Age Still Matters. Int J Mol Sci. 2024;25: pubmed publisher
Tamagawa S, Sakai D, Nojiri H, Nakamura Y, Warita T, Matsushita E, et al. SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential. Redox Biol. 2024;71:103091 pubmed publisher
Oudard S, Benhamouda N, Escudier B, Ravel P, Tran T, Levionnois E, et al. Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma. Cells. 2021;11: pubmed publisher
Adjuto Saccone M, Soubeyran P, Garcia J, Audebert S, Camoin L, Rubis M, et al. TNF-α induces endothelial-mesenchymal transition promoting stromal development of pancreatic adenocarcinoma. Cell Death Dis. 2021;12:649 pubmed publisher
Sakai D, Schol J, Bach F, Tekari A, Sagawa N, Nakamura Y, et al. Successful fishing for nucleus pulposus progenitor cells of the intervertebral disc across species. JOR Spine. 2018;1:e1018 pubmed publisher
Campanelli R, Fois G, Catarsi P, Poletto V, Villani L, Erba B, et al. Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis. PLoS ONE. 2016;11:e0156990 pubmed publisher
Wang X, Dai Z, Wu X, Wang K, Wang X. Distinct RNA transcriptome patterns are potentially associated with angiogenesis in Tie2-expressing monocytes. Gene. 2016;580:1-7 pubmed publisher
He Y, Wang C, Yu Y, Qian J, Song K, Sun Q, et al. Tie2-Expressing Monocytes Are Associated with Identification and Prognoses of Hepatitis B Virus Related Hepatocellular Carcinoma after Resection. PLoS ONE. 2015;10:e0143657 pubmed publisher
Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, et al. Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. BMC Cancer. 2014;14:939 pubmed publisher
Al ofi E, Coffelt S, Anumba D. Monocyte subpopulations from pre-eclamptic patients are abnormally skewed and exhibit exaggerated responses to Toll-like receptor ligands. PLoS ONE. 2012;7:e42217 pubmed publisher
Wang C, Tang X, Sun X, Miao Z, Lv Y, Yang Y, et al. TGF? inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy. Cell Res. 2012;22:194-207 pubmed publisher
Shantsila E, Wrigley B, Tapp L, Apostolakis S, Montoro Garcia S, Drayson M, et al. Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. J Thromb Haemost. 2011;9:1056-66 pubmed publisher
image
image 1 :
R&D Systems FAB3131A image 1
Detection of Tie-2 antibody in HUVEC Human Cells antibody by Flow Cytometry.
product information
master code :
FAB3131A
SKU :
FAB3131A
product name :
Human Tie-2 APC-conjugated Antibody
unit size :
100 Tests
description :
The Human Tie-2 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Tie-2. This antibody reacts with human. The Human Tie-2 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
Tie-2
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
83715
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Tie-2, Ala23-Lys745, Accession # AAA61139
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Tie-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tie-1, recombinant mouse Tie-2, or recombinant zebrafish Tie-2 is observed.
gene symbol :
TEK
top caption :
Detection of Tie-2 antibody in HUVEC Human Cells antibody by Flow Cytometry.
accessionNumbers :
AAA61139
applications :
Flow Cytometry
USD :
429 USD
alt names :
angiopoietin-1 receptor, CD202B, CD202b antigen, EC 2.7.10, EC 2.7.10.1, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, TEK, TEK tyrosine kinase, endothelial, Tie2, TIE-2, TIE2CD202b, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, venous malformations, multiple cutaneous and mucosal, VMCM, VMCM1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.