IFN-alpha/beta R1 PE-conjugated Antibody | R&D Systems FAB245P product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

IFN-alpha/beta R1 PE-conjugated Antibody

catalog :

FAB245P

quantity :

100 Tests

price :

419 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

85228

reactivity :

human

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Gupta S, Nakabo S, Blanco L, O Neil L, Wigerblad G, Goel R, et al. Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism. Proc Natl Acad Sci U S A. 2020;117:16481-16491 pubmed publisher
Metz P, Ching K, Xie T, Delgado Cuenca P, Niessen S, Tatlock J, et al. Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling. Cell Rep. 2020;30:1935-1950.e8 pubmed publisher
Ramachandran M, Yu D, Dyczynski M, Baskaran S, Zhang L, Lulla A, et al. Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus. Clin Cancer Res. 2017;23:1519-1530 pubmed publisher
Badr G, Saad H, Waly H, Hassan K, Abdel Tawab H, Alhazza I, et al. Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL). Cell Immunol. 2010;263:31-40 pubmed publisher
Cironi P, Swinburne I, Silver P. Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. J Biol Chem. 2008;283:8469-76 pubmed publisher

image

image 1 :

Detection of IFN-a/ss R1 antibody in U937 Human cell line antibody by Flow Cytometry.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

FAB245P

SKU :

FAB245P

product name :

IFN-alpha/beta R1 PE-conjugated Antibody

Description :

The Human IFN-alpha/beta R1 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IFN-alpha/beta R1. This antibody reacts with human. The Human IFN-alpha/beta R1 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

IFN-alpha/beta R1

category :

Primary Antibodies

unit size :

100 Tests

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

85228

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IFN-alpha/beta R1, Lys28-Lys436, Accession # AAA52730

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IFN-alpha/beta R1 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, recombinant mouse IFN-alpha/beta R2, rhIL-10 R beta , rhIL-10 R alpha , or rhIL-20 R beta .

gene symbol :

IFNAR1

accessionNumbers :

AAA52730

applications :

Flow Cytometry

USD :

419 USD

alt names :

alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFN-aR1, IFNAR1, IFNBR, IFNbR1, IFN-bR1, IFN-R-1, interferon (alpha, beta and omega) receptor 1, interferon alpha/beta receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, Type I interferon receptor 1

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

more info or order :

R&D Systems product webpage