product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TGF┐▀ RII PE-conjugated Antibody
catalog :
FAB241P-100
quantity :
100 Tests (also 25 Tests)
price :
389 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
25508
reactivity :
human
application :
flow cytometry
more info or order :
citations: 9
Reference
Awad K, Kakkola L, Julkunen I. High Glucose Increases Lactate and Induces the Transforming Growth Factor Beta-Smad 1/5 Atherogenic Pathway in Primary Human Macrophages. Biomedicines. 2024;12: pubmed publisher
Oezel L, Wohltmann M, Gondorf N, Wille J, G xfc ven I, Windolf J, et al. Dupuytren's Disease Is Mediated by Insufficient TGF-β1 Release and Degradation. Int J Mol Sci. 2023;24: pubmed publisher
Toda M, Ueno M, Yamada J, Hiraga A, Asada K, Hamuro J, et al. Quiescent innate and adaptive immune responses maintain the long-term integrity of corneal endothelium reconstituted through allogeneic cell injection therapy. Sci Rep. 2022;12:18072 pubmed publisher
Sierra Parraga J, Merino A, Eijken M, Leuvenink H, Ploeg R, Møller B, et al. Reparative effect of mesenchymal stromal cells on endothelial cells after hypoxic and inflammatory injury. Stem Cell Res Ther. 2020;11:352 pubmed publisher
Stephenson S, Care M, Fan I, Zougman A, Westhead D, Doody G, et al. Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells. J Immunol. 2019;202:1287-1300 pubmed publisher
Maeda M, Chen Y, Hayashi H, Kumagai Takei N, Matsuzaki H, Lee S, et al. Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2. Int J Oncol. 2014;45:2522-32 pubmed publisher
Miller M, Petty C, Tompkins M, Fogle J. CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGF? / GARP-mediated mechanism. Virol J. 2014;11:7 pubmed publisher
Miller M, Fogle J, Ross P, Tompkins M. Feline glycoprotein A repetitions predominant anchors transforming growth factor beta on the surface of activated CD4(+)CD25(+) regulatory T cells and mediates AIDS lentivirus-induced T cell immunodeficiency. AIDS Res Hum Retroviruses. 2013;29:641-51 pubmed publisher
Lages C, Suffia I, Velilla P, Huang B, Warshaw G, Hildeman D, et al. Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J Immunol. 2008;181:1835-48 pubmed
product information
brand :
R&D Systems
master code :
FAB241P
SKU :
FAB241P-100
product name :
Human TGF┐▀ RII PE-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
seo description :
The Human TGF¿ß RII PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to TGF-beta RII. This antibody reacts with feline,human. The Human TGF¿ß RII PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunophenotyping.
target :
TGF-beta RII
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
25508
conjugate :
Phycoerythrin
dilution :
Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TGF-beta RII, Ile24-Asp159, Accession # P37173.2
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Feline,Human
specificity :
This antibody has been validated by flow cytometry on TGF┐▀ RII-transfected cells only. In contrast to Catalog # FAB2411P, minimal staining of PBMC lymphocytes was observed with this antibody.
gene symbol :
TGFBR2
top caption :
Detection of TGF-ss RII antibody in NS0 Mouse Cell Line transfected with TGF-ss RII antibody by Flow Cytometry.
accessionNumbers :
P37173.2
applications :
Immunophenotyping,Flow Cytometry
USD :
389 USD
alt names :
AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.