product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TIM-3 PerCP-conjugated Antibody
catalog :
FAB2365C
quantity :
100 Tests
price :
489 USD
clonality :
monoclonal
host :
rat
conjugate :
PerCP
clone name :
344823
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Akagi J, Baba H. Hydrogen gas activates coenzyme Q10 to restore exhausted CD8+ T cells, especially PD-1+Tim3+terminal CD8+ T cells, leading to better nivolumab outcomes in patients with lung cancer. Oncol Lett. 2020;20:258 pubmed publisher
Mateus J, Pérez Antón E, Lasso P, Egui A, Roa N, Carrilero B, et al. Antiparasitic Treatment Induces an Improved CD8+ T Cell Response in Chronic Chagasic Patients. J Immunol. 2017;198:3170-3180 pubmed publisher
Lasso P, Mateus J, Pavía P, Rosas F, Roa N, Thomas M, et al. Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. J Immunol. 2015;195:3748-58 pubmed publisher
Kared H, Saeed S, Klein M, Shoukry N. CD127 expression, exhaustion status and antigen specific proliferation predict sustained virologic response to IFN in HCV/HIV co-infected individuals. PLoS ONE. 2014;9:e101441 pubmed publisher
product information
master code :
FAB2365C
SKU :
FAB2365C
product name :
Human TIM-3 PerCP-conjugated Antibody
unit size :
100 Tests
description :
The Human TIM-3 PerCP-conjugated Antibody from R&D Systems is a rat monoclonal antibody to TIM-3. This antibody reacts with human. The Human TIM-3 PerCP-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
TIM-3
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
344823
conjugate :
PerCP (Peridinin-chlorophyll Protein Complex)
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TIM-3, Ser22-Arg200, Accession # Q8TDQ0.2
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human TIM-3 in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) TIM-1, rhTIM-4, recombinant mouse (rm) TIM-1, rmTIM-2, rmTIM-3, rmTIM-5, or rmTIM-6.
gene symbol :
HAVCR2
top caption :
Detection of TIM-3 antibody in Human Blood Monocytes antibody by Flow Cytometry.
accessionNumbers :
Q8TDQ0.2
applications :
Flow Cytometry
extended description :
Clone 344823 was used by HLDA to establish CD designation
USD :
489 USD
product details :
Clone 344823 was used by HLDA to establish CD designation
alt names :
CD366, FLJ14428, HAVcr-2, HAVCR2, hepatitis A virus cellular receptor 2, kidney injury molecule-3, KIM-3, SPTCL, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain-containing protein 3, TIM 3, Tim-3, TIM3, TIM3 T-cell membrane protein 3, TIMD3, TIMD-3, TIMD3KIM-3
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.