product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human IL-4R alpha APC-conjugated Antibody
catalog :
FAB230A-100
quantity :
100 Tests (also 25 Tests)
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
25463
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Sukumaran S, Watanabe N, Bajgain P, Raja K, Mohammed S, Fisher W, et al. Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment. Cancer Discov. 2018;8:972-987 pubmed publisher
Zilio S, Vella J, De La Fuente A, Daftarian P, Weed D, Kaifer A, et al. 4PD Functionalized Dendrimers: A Flexible Tool for In Vivo Gene Silencing of Tumor-Educated Myeloid Cells. J Immunol. 2017;198:4166-4177 pubmed publisher
Warren K, Fang X, Gowda N, Thompson J, Heller N. The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2. J Biol Chem. 2016;291:24922-24930 pubmed
Bailur J, Gueckel B, Derhovanessian E, Pawelec G. Presence of circulating Her2-reactive CD8 + T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients. Breast Cancer Res. 2015;17:34 pubmed publisher
Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, et al. Absence of a role for interleukin-13 in inflammatory bowel disease. Eur J Immunol. 2014;44:370-85 pubmed publisher
product information
master code :
FAB230A
SKU :
FAB230A-100
product name :
Human IL-4R alpha APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human IL-4R alpha APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-4R alpha. This antibody reacts with human. The Human IL-4R alpha APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
IL-4R alpha
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
25463
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-4 R, Gly24-His232, Accession # P24394
isotype :
IgG2a
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human IL-4 R alpha in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-9 R, recombinant mouse IL-4 R, rhIL-5 R alpha , rhIL-5 R▀, rhIL-13 R alpha 1, or rhIL-13 R alpha 2 is observed.
gene symbol :
IL4R
top caption :
Detection of IL-4 Ra antibody in Daudi Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P24394
applications :
Flow Cytometry
USD :
449 USD
alt names :
CD124, CD124 antigen, IL-4 R alpha, IL-4 receptor subunit alpha, IL4R, IL4R alpha, IL-4R subunit alpha, IL-4RA, IL4RACD124, IL-4R-alpha, interleukin 4 receptor, interleukin-4 receptor alpha chain, interleukin-4 receptor subunit alpha
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.