Human gp130 PE-conjugated Antibody | R&D Systems FAB228P-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human gp130 PE-conjugated Antibody

catalog :

FAB228P-100

quantity :

100 Tests (also 25 Tests)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

28126

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Suzuki H, Mitsunaga S, Ikeda M, Aoyama T, Yoshizawa K, Yamaguchi M, et al. Interleukin 6/gp130 axis promotes neural invasion in pancreatic cancer. Cancer Med. 2022;11:5001-5012 pubmed publisher
Kubala M, Punj V, Placencio Hickok V, Fang H, Fernandez G, Sposto R, et al. Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer. Cell Rep. 2018;25:2177-2191.e7 pubmed publisher
Ray S, Ju X, Sun H, Finnerty C, Herndon D, Brasier A. The IL-6 trans-signaling-STAT3 pathway mediates ECM and cellular proliferation in fibroblasts from hypertrophic scar. J Invest Dermatol. 2013;133:1212-20 pubmed publisher
Cocco C, Di Carlo E, Zupo S, Canale S, Zorzoli A, Ribatti D, et al. Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo. Leukemia. 2012;26:1365-74 pubmed publisher
Larsen J, Hansen M, Møller B, Madsen P, Scheller J, Nielsen M, et al. Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer. Mol Cell Biol. 2010;30:4175-87 pubmed publisher
Marino M, Scuderi F, Provenzano C, Scheller J, Rose John S, Bartoccioni E. IL-6 regulates MCP-1, ICAM-1 and IL-6 expression in human myoblasts. J Neuroimmunol. 2008;196:41-8 pubmed publisher

product information

master code :

FAB228P

SKU :

FAB228P-100

product name :

Human gp130 PE-conjugated Antibody

unit size :

100 Tests (also 25 Tests)

description :

The Human gp130 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to gp130/CD130. This antibody reacts with human. The Human gp130 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry.

target :

gp130

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

28126

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human gp130 extracellular domain

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human gp130 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R, rhIL-4 R, or rhIL-6 R is observed.

gene symbol :

IL6ST

top caption :

Detection of gp130 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

applications :

Flow Cytometry,Immunocytochemistry

USD :

409 USD

alt names :

CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage