product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-2 R▀ PE-conjugated Antibody
catalog :
FAB224P
quantity :
100 Tests
price :
389 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
27302
reactivity :
human
application :
flow cytometry
more info or order :
citations: 6
Reference
Devocelle A, Lecru L, Francois H, Desterke C, Gallerne C, Eid P, et al. Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis. Int J Cell Biol. 2019;2019:9151394 pubmed publisher
Arneja A, Johnson H, Gabrovsek L, Lauffenburger D, White F. Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration. J Immunol. 2014;192:123-35 pubmed publisher
Pandya A, Al Jaderi Z, Høglund R, Holmøy T, Harbo H, Norgauer J, et al. Identification of human NK17/NK1 cells. PLoS ONE. 2011;6:e26780 pubmed publisher
Ogbomo H, Michaelis M, Altenbrandt B, Doerr H, Cinatl J. A novel immunomodulatory mechanism of ribavirin in suppressing natural killer cell function. Biochem Pharmacol. 2010;79:188-97 pubmed publisher
Zheng C, Jones G, Shi M, Wiseman J, Marr K, Berenger B, et al. Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients. J Immunol. 2008;180:7221-9 pubmed
Ogbomo H, Michaelis M, Kreuter J, Doerr H, Cinatl J. Histone deacetylase inhibitors suppress natural killer cell cytolytic activity. FEBS Lett. 2007;581:1317-22 pubmed
product information
master code :
FAB224P
SKU :
FAB224P
product name :
Human IL-2 R▀ PE-conjugated Antibody
unit size :
100 Tests
description :
The Human IL-2 Rß PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-2 R beta. This antibody reacts with human. The Human IL-2 Rß PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
IL-2 R beta
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
27302
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-2 R▀, Ala27-Asp239, Accession # NP_000869
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human IL-2 R▀ in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rh gamma c, rhIL-4 R, or rhIL-6 R is observed.
gene symbol :
IL2RB
top caption :
Detection of IL-2 Rss antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
accessionNumbers :
NP_000869
applications :
Flow Cytometry
USD :
389 USD
alt names :
CD122, CD122 antigen, high affinity IL-2 receptor beta subunit, High affinity IL-2 receptor subunit beta, IL-15 R beta, IL-2 receptor subunit beta, IL2R beta, IL-2R subunit beta, IL2RB, IL-2RB, interleukin 15 receptor, beta, interleukin 2 receptor, beta, interleukin-2 receptor subunit beta, P70-75, p75
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.