Mouse CXCR2/IL-8RB PE-conjugated Antibody | R&D Systems FAB2164P-025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CXCR2/IL-8RB PE-conjugated Antibody

catalog :

FAB2164P-025

quantity :

25 Tests (also 100 Tests)

price :

149 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

242216

reactivity :

human, mouse

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 24

Reference
Brennan F, Jogia T, Gillespie E, Blomster L, Li X, Nowlan B, et al. Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI Insight. 2019;4: pubmed publisher
Kumar V, Donthireddy L, Marvel D, Condamine T, Wang F, Lavilla Alonso S, et al. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors. Cancer Cell. 2017;32:654-668.e5 pubmed publisher
Xu J, Guardado J, Hoffman R, Xu H, Namas R, Vodovotz Y, et al. IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model. PLoS Med. 2017;14:e1002365 pubmed publisher
Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed publisher
Wang D, Sun H, Wei J, Cen B, DuBois R. CXCL1 Is Critical for Premetastatic Niche Formation and Metastasis in Colorectal Cancer. Cancer Res. 2017;77:3655-3665 pubmed publisher
Lee W, Yan J, Kang J, Zhang Q, Choi W, Kim L, et al. Mincle activation enhances neutrophil migration and resistance to polymicrobial septic peritonitis. Sci Rep. 2017;7:41106 pubmed publisher
Sharif S, Nakatani Y, Wise L, Corbett M, Real N, Stuart G, et al. A Broad-Spectrum Chemokine-Binding Protein of Bovine Papular Stomatitis Virus Inhibits Neutrophil and Monocyte Infiltration in Inflammatory and Wound Models of Mouse Skin. PLoS ONE. 2016;11:e0168007 pubmed publisher
Bueno Silva B, Franchin M, Alves C, Denny C, Colón D, Cunha T, et al. Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process. Phytomedicine. 2016;23:1583-1590 pubmed publisher
Li Y, Huang J, Foley N, Xu Y, Li Y, Pan J, et al. B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration. Sci Rep. 2016;6:31284 pubmed publisher
Li J, Wu S, Tang H, Huang W, Wang L, Zhou H, et al. Long-term effects of acupuncture treatment on airway smooth muscle in a rat model of smoke-induced chronic obstructive pulmonary disease. Acupunct Med. 2016;34:107-13 pubmed publisher
Citro A, Valle A, Cantarelli E, Mercalli A, Pellegrini S, Liberati D, et al. CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice. Diabetes. 2015;64:1329-40 pubmed publisher
Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, et al. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunol. 2014;7:1079-93 pubmed publisher
Wang P, Bai F, Zenewicz L, Dai J, Gate D, Cheng G, et al. IL-22 signaling contributes to West Nile encephalitis pathogenesis. PLoS ONE. 2012;7:e44153 pubmed publisher
Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, et al. CRTH2 is a critical regulator of neutrophil migration and resistance to polymicrobial sepsis. J Immunol. 2012;188:5655-64 pubmed publisher
Spiller F, Carlos D, Souto F, de Freitas A, Soares F, Vieira S, et al. ?1-Acid glycoprotein decreases neutrophil migration and increases susceptibility to sepsis in diabetic mice. Diabetes. 2012;61:1584-91 pubmed publisher
Salvucci O, Jiang K, Gasperini P, Maric D, Zhu J, Sakakibara S, et al. MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1. Haematologica. 2012;97:818-26 pubmed publisher
Chou R, Kim N, Sadik C, Seung E, Lan Y, Byrne M, et al. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis. Immunity. 2010;33:266-78 pubmed publisher
Zarbock A, Bishop J, Muller H, Schmolke M, Buschmann K, Van Aken H, et al. Chemokine homeostasis vs. chemokine presentation during severe acute lung injury: the other side of the Duffy antigen receptor for chemokines. Am J Physiol Lung Cell Mol Physiol. 2010;298:L462-71 pubmed publisher
Lee S, Ju S, Sung B, Heo S, Cho H, Lee E, et al. Stimulation of the molecule 4-1BB enhances host defense against Listeria monocytogenes infection in mice by inducing rapid infiltration and activation of neutrophils and monocytes. Infect Immun. 2009;77:2168-76 pubmed publisher
Calderon B, Suri A, Miller M, Unanue E. Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules. Proc Natl Acad Sci U S A. 2008;105:6121-6 pubmed publisher
Mayr F, Spiel A, Leitner J, Firbas C, Kliegel T, Jilma Stohlawetz P, et al. Duffy antigen modifies the chemokine response in human endotoxemia. Crit Care Med. 2008;36:159-65 pubmed
Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T. Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice. Eur J Immunol. 2007;37:2753-63 pubmed
Bestebroer J, Poppelier M, Ulfman L, Lenting P, Denis C, Van Kessel K, et al. Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling. Blood. 2007;109:2936-43 pubmed
Panopoulos A, Zhang L, Snow J, Jones D, Smith A, El Kasmi K, et al. STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils. Blood. 2006;108:3682-90 pubmed

product information

master code :

FAB2164P

SKU :

FAB2164P-025

product name :

Mouse CXCR2/IL-8RB PE-conjugated Antibody

unit size :

25 Tests (also 100 Tests)

description :

The Mouse CXCR2/IL-8RB PE-conjugated Antibody from R&D Systems is a rat monoclonal antibody to CXCR2/IL-8RB. This antibody reacts with human,mouse. The Mouse CXCR2/IL-8RB PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

CXCR2/IL-8RB

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

242216

conjugate :

Phycoerythrin

host :

Rat

immunogen :

C6 rat glioma cell line transfected with mouse CXCR2, Met1-Leu359, Accession # P35343

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Stains mouse CXCR2-transfected cells but not CXCR1 transfectants.

gene symbol :

CXCR2

top caption :

Detection of CXCR2/IL-8 RB antibody in Mouse Splenocytes antibody by Flow Cytometry.

accessionNumbers :

P35343

applications :

Flow Cytometry

USD :

149 USD

alt names :

CD182, CD182 antigen, CDw128b, chemokine (C-X-C motif) receptor 2, chemokine (CXC) receptor 2, CMKAR2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CXCR2 gene for IL8 receptor type B, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8 RB, IL-8 receptor type 2, IL-8R B, IL8R2, IL8RA, IL8RB, interleukin 8 receptor B, interleukin 8 receptor type 2, interleukin-8 receptor type B

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage