product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human LDLR PE-conjugated Antibody
catalog :
FAB2148P
quantity :
100 Tests
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
472413
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, et al. Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance. EMBO Rep. 2022;:e53373 pubmed publisher
Ramanathan A, Gusarova V, Stahl N, Gurnett Bander A, Kyratsous C. Alirocumab, a Therapeutic Human Antibody to PCSK9, Does Not Affect CD81 Levels or Hepatitis C Virus Entry and Replication into Hepatocytes. PLoS ONE. 2016;11:e0154498 pubmed publisher
Le Q, Blanchet M, Seidah N, Labonté P. Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9. J Biol Chem. 2015;290:23385-400 pubmed publisher
Mercer J, Argus J, Crabtree D, KEENAN M, Wilks M, Chi J, et al. Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis. PLoS ONE. 2015;10:e0129776 pubmed publisher
product information
master code :
FAB2148P
SKU :
FAB2148P
product name :
Human LDLR PE-conjugated Antibody
unit size :
100 Tests
description :
The Human LDLR PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to LDLR. This antibody reacts with human. The Human LDLR PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
LDLR
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
472413
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human LDL R, Ala22-Arg788, Accession # P01130
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human LDL R in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) LDL R, recombinant human LRP-5, or rmLRP-6 is observed.
gene symbol :
LDLR
top caption :
Detection of LDL R antibody in HepG2 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P01130
applications :
Flow Cytometry
USD :
449 USD
alt names :
FH, FHC, LDL R, LDL receptor, LDLCQ2, low density lipoprotein receptor, low-density lipoprotein receptor, low-density lipoprotein receptor class A domain-containing protein 3
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.