product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human LDLR APC-conjugated Antibody
catalog :
FAB2148A
quantity :
100 Tests
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
472413
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Babl N, Hofbauer J, Matos C, Voll F, Menevse A, Rechenmacher M, et al. Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model. Front Oncol. 2023;13:1107484 pubmed publisher
Chemello K, Beesk xe9 S, Trang Tran T, Blanchard V, Villard E, Poirier B, et al. Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab. JACC Basic Transl Sci. 2020;5:549-557 pubmed publisher
Giugliano S, Petroff M, Warren B, Jasti S, Linscheid C, Ward A, et al. Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. J Immunol. 2015;195:3737-47 pubmed publisher
Le Q, Blanchet M, Seidah N, Labonté P. Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9. J Biol Chem. 2015;290:23385-400 pubmed publisher
Baldwin K, Urbinati F, Romero Z, Campo Fernandez B, Kaufman M, Cooper A, et al. Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy. Stem Cells. 2015;33:1532-42 pubmed publisher
product information
master code :
FAB2148A
SKU :
FAB2148A
product name :
Human LDLR APC-conjugated Antibody
unit size :
100 Tests
description :
The Human LDLR APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to LDLR. This antibody reacts with human. The Human LDLR APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
LDLR
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
472413
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human LDL R, Ala22-Arg788, Accession # P01130
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human LDL R in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) LDL R, recombinant human LRP-5, or rmLRP-6 is observed.
gene symbol :
LDLR
top caption :
Detection of LDL R antibody in HepG2 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P01130
applications :
Flow Cytometry
USD :
459 USD
alt names :
FH, FHC, LDL R, LDL receptor, LDLCQ2, low density lipoprotein receptor, low-density lipoprotein receptor, low-density lipoprotein receptor class A domain-containing protein 3
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.