Human TNF-alpha Membrane Form Fluorescein-conjugated Antibody | R&D Systems FAB210F-050 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TNF-alpha Membrane Form Fluorescein-conjugated Antibody

catalog :

FAB210F-050

quantity :

50 Tests (also 25 Tests)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

6401

reactivity :

human

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Nguyen D, Ehrenstein M. Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF-TNF-RII binding in rheumatoid arthritis. J Exp Med. 2016;213:1241-53 pubmed publisher
Moreira Tabaka H, Peluso J, Vonesch J, Hentsch D, Kessler P, Reimund J, et al. Unlike for human monocytes after LPS activation, release of TNF-? by THP-1 cells is produced by a TACE catalytically different from constitutive TACE. PLoS ONE. 2012;7:e34184 pubmed publisher
Lee S, Cherla R, Tesh V. Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1. Infect Immun. 2007;75:1291-302 pubmed
Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, et al. Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. Crit Care Med. 2005;33:1359-64 pubmed
Lopez M, Rios E, Schlesinger L, Olivares M, Nunez M, Munoz C. Tumour necrosis factor-alpha transcription in transferrin-stimulated human blood mononuclear cells: is transferrin receptor involved in the signalling mechanism?. Br J Haematol. 2003;120:829-35 pubmed

product information

brand :

R&D Systems

master code :

FAB210F

SKU :

FAB210F-050

product name :

Human TNF-alpha Membrane Form Fluorescein-conjugated Antibody

unit size :

50 Tests (also 25 Tests)

seo description :

The Human TNF-alpha Membrane Form Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to TNF-alpha. This antibody reacts with human. The Human TNF-alpha Membrane Form Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

TNF-alpha

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

6401

conjugate :

Fluorescein

dilution :

Flow Cytometry 10 uL/10^6 cells

host :

Mouse

immunogen :

E. coli -derived recombinant human TNF-alpha , Gly57-Leu233 (predicted), Accession # P01375

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects cell surface expressed TNF-alpha (membrane and receptor bound forms) by flow cytometry. Detects human TNF-alpha in direct ELISAs and Western blots. In direct ELISAs, approximately 25-50% cross-reactivity with recombinant porcine TNF-alpha and recombinant rhesus macaque TNF-alpha is observed but no cross-reactivity with recombinant cotton rat TNF-alpha , recombinant rat TNF-alpha , recombinant human (rh) LT alpha 1í▀2, rhLT alpha 2í▀1, rhAPRIL, rhBAFF, rhEDA-A2, recombinant mouse EDA, rhFas Ligand, rhLIGHT, rhOX40 Ligand, rhTRAIL, rhTRANCE, rhTWEAK, or rhVEGI is observed.

gene symbol :

TNF

accessionNumbers :

P01375

applications :

Flow Cytometry

USD :

459 USD

alt names :

APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage