product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human KIR2DL3/CD158b2 PE-conjugated Antibody
catalog :
FAB2014P-025
quantity :
25 Tests (also 100 Tests)
price :
149 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
180701
reactivity :
human
application :
flow cytometry, FACS
more info or order :
R&D Systems product webpage
citations: 11
Reference
Lee S, Chae S, Jang I, Oh S, Kim S, Lee S, et al. B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies. EBioMedicine. 2024;110:105459 pubmed publisher
Goldenson B, Zhu H, Wang Y, Heragu N, Bernareggi D, Ruiz Cisneros A, et al. Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles. Front Immunol. 2020;11:561553 pubmed publisher
Samarani S, Sagala P, Jantchou P, Grimard G, Faure C, Deslandres C, et al. Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients. Mediators Inflamm. 2020;2020:6401969 pubmed publisher
Lisovsky I, Kant S, Tremblay McLean A, Isitman G, Kiani Z, Dupuy F, et al. Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC. J Leukoc Biol. 2019;105:551-563 pubmed publisher
Tschan Plessl A, Stern M, Schmied L, Retiere C, Hirsch H, Garzoni C, et al. Human Cytomegalovirus Infection Enhances NK Cell Activity In Vitro. Transplant Direct. 2016;2:e89 pubmed
Li W, Jiang Y, Wang X, Jin J, Qi Y, Chi X, et al. Natural Killer p46 Controls Hepatitis B Virus Replication and Modulates Liver Inflammation. PLoS ONE. 2015;10:e0135874 pubmed publisher
Holmes T, Wilson E, Black E, Benest A, Vaz C, Tan B, et al. Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT. Proc Natl Acad Sci U S A. 2014;111:E5688-96 pubmed publisher
Hu X, Jiang Y, Li X, Gao Y, Guo X, Chi X, et al. Long-term effect on natural killer cells by interferon-α therapy on the outcomes of HCV infection. J Interferon Cytokine Res. 2014;34:366-75 pubmed publisher
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol. 2013;43:480-7 pubmed publisher
Yu J, Mitsui T, Wei M, Mao H, Butchar J, Shah M, et al. NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human. J Clin Invest. 2011;121:1456-70 pubmed publisher
Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, et al. Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Blood. 2008;111:3155-62 pubmed publisher
product information
master code :
FAB2014P
SKU :
FAB2014P-025
product name :
Human KIR2DL3/CD158b2 PE-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Human KIR2DL3/CD158b2 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to KIR2DL3/CD158b2. This antibody reacts with human. The Human KIR2DL3/CD158b2 PE-conjugated Antibody has been validated for the following applications: FACS,Flow Cytometry.
target :
KIR2DL3/CD158b2
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
180701
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human KIR2DL3/CD158b2, Accession # P43628
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human KIR2DL3/CD158b2. Stains BaF3 cells transfected with human KIR2DL3 in flow cytometry. Does not stain BaF3 cells transfected with KIR2DL1, 2DL2, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
gene symbol :
KIR2DL3
top caption :
Detection of KIR2DL3/CD158b2 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
P43628
applications :
FACS,Flow Cytometry
USD :
149 USD
alt names :
CD158 antigen-like family member B2, CD158b2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, nkat2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.