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company name :
R&D Systems
product type :
antibody
product name :
Human CCR7 PE-conjugated Antibody
catalog :
FAB197P-100
quantity :
100 Tests (also 25 Tests)
price :
359 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
150503
reactivity :
human, rhesus macaque
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 72
Reference
Cargill T, Barnes E, Rispens T, Culver E. The Differential Complement, Fc and Chemokine Receptor Expression of B Cells in IgG4-Related Pancreatobiliary Disease and Primary Sclerosing Cholangitis and Its Relevance for Targeting B Cell Pathways in Disease. Biomedicines. 2024;12: pubmed publisher
Sadeghi L, Wright A. GSK-J4 Inhibition of KDM6B Histone Demethylase Blocks Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells by Modulating NF-κB Signaling. Cells. 2023;12: pubmed publisher
Huuhtanen J, Kasanen H, Peltola K, L xf6 nnberg T, Glumoff V, Br xfc ck O, et al. Single-cell characterization of anti-LAG-3 and anti-PD-1 combination treatment in patients with melanoma. J Clin Invest. 2023;133: pubmed publisher
Huuhtanen J, Ilander M, Yadav B, Dufva O, L xe4 hteenm xe4 ki H, Kasanen T, et al. IFN-α with dasatinib broadens the immune repertoire in patients with chronic-phase chronic myeloid leukemia. J Clin Invest. 2022;132: pubmed publisher
Koido S, Horiuchi S, Kan S, Bito T, Ito Z, Uchiyama K, et al. The stimulatory effect of fusobacteria on dendritic cells under aerobic or anaerobic conditions. Sci Rep. 2022;12:10698 pubmed publisher
Mateu Albero T, Marcos Jiménez A, Wissmann S, Loscertales J, Terr xf3 n F, Stein J, et al. Ibrutinib Does Not Impact CCR7-Mediated Homeostatic Migration in T-Cells from Chronic Lymphocytic Leukemia Patients. Cancers (Basel). 2022;14: pubmed publisher
Del Molino Del Barrio I, Meeson A, Cooke K, Malki M, Barron Millar B, Kirby J, et al. Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
Hirama T, Tokita S, Nakatsugawa M, Murata K, Nannya Y, Matsuo K, et al. Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch repair-deficient colorectal cancer tissue. JCI Insight. 2021;6: pubmed publisher
Kim D, Park G, Huuhtanen J, Lundgren S, Khajuria R, Hurtado A, et al. Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease. Nat Commun. 2020;11:2246 pubmed publisher
Tyrinova T, Leplina O, Mishinov S, Tikhonova M, Dolgova E, Proskurina A, et al. Defective Regulation of Membrane TNFα Expression in Dendritic Cells of Glioblastoma Patients Leads to the Impairment of Cytotoxic Activity against Autologous Tumor Cells. Int J Mol Sci. 2020;21: pubmed publisher
Kobayashi Y, Yamada D, Kawai T, Sato Y, Teshima T, Yamada Y, et al. Different immunological effects of the molecular targeted agents sunitinib, everolimus and temsirolimus in patients with renal cell carcinoma. Int J Oncol. 2020;56:999-1013 pubmed publisher
Kurihara K, Fujiyama T, Phadungsaksawasdi P, Ito T, Tokura Y. Significance of IL-17A-producing CD8+CD103+ skin resident memory T cells in psoriasis lesion and their possible relationship to clinical course. J Dermatol Sci. 2019;95:21-27 pubmed publisher
Jimenez Vera E, Chew Y, Nicholson L, Burns H, Anderson P, Chen H, et al. Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients. PLoS ONE. 2019;14:e0217163 pubmed publisher
Hohtari H, Brück O, Blom S, Turkki R, Sinisalo M, Kovanen P, et al. Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL. Leukemia. 2019;: pubmed publisher
Wu C, Yang P, Liu H, Xiao W, Zhao L. Increased frequency of CCR7+CD4+ T cells from patients with primary Sjögren's syndrome: An indicator of disease activity rather than of damage severity. Cytokine. 2018;110:9-17 pubmed publisher
Giacomet V, Masetti M, Nannini P, Forlanini F, Clerici M, Zuccotti G, et al. Humoral and cell-mediated immune responses after a booster dose of HBV vaccine in HIV-infected children, adolescents and young adults. PLoS ONE. 2018;13:e0192638 pubmed publisher
Ge C, Li R, Song H, Geng T, Yang J, Tan Q, et al. Phase I clinical trial of a novel autologous modified-DC vaccine in patients with resected NSCLC. BMC Cancer. 2017;17:884 pubmed publisher
Sander J, Schmidt S, Cirovic B, McGovern N, Papantonopoulou O, Hardt A, et al. Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 2017;47:1051-1066.e12 pubmed publisher
Talotta R, Berzi A, Doria A, Batticciotto A, Ditto M, Atzeni F, et al. The Immunogenicity of Branded and Biosimilar Infliximab in Rheumatoid Arthritis According to Th9-Related Responses. Int J Mol Sci. 2017;18: pubmed publisher
Thitilertdecha P, Khowawisetsut L, Ammaranond P, Poungpairoj P, Tantithavorn V, Onlamoon N. Impact of Vaccination on Distribution of T Cell Subsets in Antiretroviral-Treated HIV-Infected Children. Dis Markers. 2017;2017:5729639 pubmed publisher
Barisa M, Kramer A, Majani Y, Moulding D, Saraiva L, Bajaj Elliott M, et al. E. coli promotes human Vγ9Vδ2 T cell transition from cytokine-producing bactericidal effectors to professional phagocytic killers in a TCR-dependent manner. Sci Rep. 2017;7:2805 pubmed publisher
Li S, Sullivan N, Rouphael N, Yu T, Banton S, Maddur M, et al. Metabolic Phenotypes of Response to Vaccination in Humans. Cell. 2017;169:862-877.e17 pubmed publisher
Breuer O, Daum H, Cohen Cymberknoh M, Unger S, Shoseyov D, Stepensky P, et al. Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis. Respir Med. 2017;126:39-45 pubmed publisher
Berry N, Manoussaka M, Ham C, Ferguson D, Tudor H, Mattiuzzo G, et al. Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine. PLoS Pathog. 2016;12:e1006083 pubmed publisher
Kho M, Zuijderwijk J, van der Eijk A, de Kuiper R, Boer Verschragen M, Weimar W, et al. Humoral and cellular response after varicella vaccination in VZV IgG seronegative kidney transplant candidates. Vaccine. 2017;35:71-76 pubmed publisher
Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, et al. Cognate HLA absence in trans diminishes human NK cell education. J Clin Invest. 2016;126:3772-3782 pubmed publisher
Smith K, Mailliard R, Piazza P, Fischer W, Korber B, Fecek R, et al. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. MBio. 2016;7: pubmed publisher
Massa C, Thomas C, Wang E, Marincola F, Seliger B. Different maturation cocktails provide dendritic cells with different chemoattractive properties. J Transl Med. 2015;13:175 pubmed publisher
Billingsley J, Rajakumar P, Connole M, Salisch N, Adnan S, Kuzmichev Y, et al. Characterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profiling. PLoS Pathog. 2015;11:e1004740 pubmed publisher
Seifert M, Przekopowitz M, Taudien S, Lollies A, Ronge V, Drees B, et al. Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions. Proc Natl Acad Sci U S A. 2015;112:E546-55 pubmed publisher
Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
Dimeloe S, Frick C, Fischer M, Gubser P, Razik L, Bantug G, et al. Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis. Eur J Immunol. 2014;44:3614-20 pubmed publisher
Kreutzman A, Ilander M, Porkka K, Vakkila J, Mustjoki S. Dasatinib promotes Th1-type responses in granzyme B expressing T-cells. Oncoimmunology. 2014;3:e28925 pubmed
Koido S, Homma S, Okamoto M, Takakura K, Mori M, Yoshizaki S, et al. Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer. Clin Cancer Res. 2014;20:4228-39 pubmed publisher
Melum G, Farkas L, Scheel C, Van Dieren B, Gran E, Liu Y, et al. A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa. J Allergy Clin Immunol. 2014;134:613-621.e7 pubmed publisher
Le Brocq M, Fraser A, Cotton G, Woznica K, McCulloch C, Hewitt K, et al. Chemokines as novel and versatile reagents for flow cytometry and cell sorting. J Immunol. 2014;192:6120-6130 pubmed publisher
Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, et al. IL-2 phosphorylates STAT5 to drive IFN-? production and activation of human dendritic cells. J Immunol. 2014;192:5660-70 pubmed publisher
Wolfl M, Greenberg P. Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells. Nat Protoc. 2014;9:950-66 pubmed publisher
Zou Y, Li F, Hou W, Sampath P, Zhang Y, Thorne S. Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells. Br J Cancer. 2014;110:1992-9 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Ilander M, Kreutzman A, Rohon P, Melo T, Faber E, Porkka K, et al. Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-? monotherapy. PLoS ONE. 2014;9:e87794 pubmed publisher
Qiu X, Audet J, Wong G, Fernando L, Bello A, Pillet S, et al. Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb. Sci Rep. 2013;3:3365 pubmed publisher
Ho L, Yit P, Ng L, Linn Y, Zhao Y, Sun L, et al. The road to memory: an early rest for the long journey. J Immunol. 2013;191:5603-14 pubmed publisher
Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, THADHANI R, et al. Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors. J Immunol. 2013;190:3939-48 pubmed publisher
Schure R, de Rond L, Oztürk K, Hendrikx L, Sanders E, Berbers G, et al. Pertussis circulation has increased T-cell immunity during childhood more than a second acellular booster vaccination in Dutch children 9 years of age. PLoS ONE. 2012;7:e41928 pubmed publisher
Wang W, Yu D, Sarnaik A, Yu B, Hall M, Morelli D, et al. Biomarkers on melanoma patient T cells associated with ipilimumab treatment. J Transl Med. 2012;10:146 pubmed publisher
Badr G, Lefevre E, Mohany M. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE. 2011;6:e23741 pubmed publisher
Singh H, Figliola M, Dawson M, Huls H, Olivares S, Switzer K, et al. Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies. Cancer Res. 2011;71:3516-27 pubmed publisher
Amarnath S, Flomerfelt F, Costanzo C, Foley J, Mariotti J, Konecki D, et al. Rapamycin generates anti-apoptotic human Th1/Tc1 cells via autophagy for induction of xenogeneic GVHD. Autophagy. 2010;6:523-41 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, et al. CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses. J Immunol. 2010;184:1102-10 pubmed publisher
Manuri P, Wilson M, Maiti S, Mi T, Singh H, Olivares S, et al. piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies. Hum Gene Ther. 2010;21:427-37 pubmed publisher
Damas J, Landrø L, Fevang B, Heggelund L, Tjønnfjord G, Fløisand Y, et al. Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication. Clin Exp Immunol. 2009;157:400-7 pubmed publisher
Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol. 2009;10:857-63 pubmed publisher
Ahern D, Lloyd C, Robinson D. Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors. Allergy. 2009;64:1121-9 pubmed publisher
Ansén S, Butler M, Berezovskaya A, Murray A, Stevenson K, Nadler L, et al. Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21. Clin Cancer Res. 2008;14:6125-36 pubmed publisher
Moir S, Ho J, Malaspina A, Wang W, DiPoto A, O Shea M, et al. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med. 2008;205:1797-805 pubmed publisher
Jasny E, Eisenblatter M, Mätz Rensing K, Tenner Racz K, Tenbusch M, Schrod A, et al. IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation. J Immunol. 2008;180:6629-39 pubmed
Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, et al. Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells. FASEB J. 2008;22:2747-57 pubmed publisher
Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, et al. CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1. Cancer Res. 2008;68:790-9 pubmed publisher
Pokkali S, Das S, R L. Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. Cytokine. 2008;41:307-14 pubmed publisher
Badr G, Borhis G, Lefevre E, Chaoul N, Deshayes F, Dessirier V, et al. BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells. Blood. 2008;111:2744-54 pubmed publisher
Acosta Rodriguez E, Napolitani G, Lanzavecchia A, Sallusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol. 2007;8:942-9 pubmed
Lecureuil C, Combadiere B, Mazoyer E, Bonduelle O, Samri A, Autran B, et al. Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients. Blood. 2007;109:3649-57 pubmed
Kaur A, Sanford H, Garry D, Lang S, Klumpp S, Watanabe D, et al. Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus. Virology. 2007;357:199-214 pubmed
Eksteen B, Miles A, Curbishley S, Tselepis C, Grant A, Walker L, et al. Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10. J Immunol. 2006;177:593-603 pubmed
Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson P, et al. The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood. 2006;108:947-55 pubmed
Muller A, Sonkoly E, Eulert C, Gerber P, Kubitza R, Schirlau K, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer. 2006;118:2147-57 pubmed
Corcione A, Casazza S, Ferretti E, Giunti D, Zappia E, Pistorio A, et al. Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis. Proc Natl Acad Sci U S A. 2004;101:11064-9 pubmed
Godfrey W, Ge Y, Spoden D, Levine B, June C, Blazar B, et al. In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood. 2004;104:453-61 pubmed
Liu L, Jarjour N, Busse W, Kelly E. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge. J Allergy Clin Immunol. 2003;112:556-62 pubmed
Kivisakk P, Mahad D, Callahan M, Trebst C, Tucky B, Wei T, et al. Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin. Proc Natl Acad Sci U S A. 2003;100:8389-94 pubmed
image
image 1 :
R&D Systems FAB197P-100 image 1
Detection of CCR7 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
product information
master code :
FAB197P
SKU :
FAB197P-100
product name :
Human CCR7 PE-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human CCR7 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCR7. This antibody reacts with human,primate,primate - macaca mulatta (rhesus macaque). The Human CCR7 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry.
target :
CCR7
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
150503
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Human CCR7 transfectants, Met1-Pro378, Accession # AAA58615
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Primate,Primate - Macaca mulatta (Rhesus Macaque)
specificity :
Detects human CCR7.
gene symbol :
CCR7
top caption :
Detection of CCR7 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
accessionNumbers :
AAA58615
applications :
Flow Cytometry,Immunocytochemistry
extended description :
Clone 150503 was used by HLDA to establish CD designation
USD :
359 USD
product details :
Clone 150503 was used by HLDA to establish CD designation
alt names :
BLR2, BLR2C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR7, CCR-7, CD197, CD197 antigen, CDw197, CDw197CC chemokine receptor 7, chemokine (C-C motif) receptor 7, CMKBR7, CMKBR7chemokine (C-C) receptor 7, EBI1, EBI1EBV-induced G protein-coupled receptor 1, EBV-induced G-protein coupled receptor 1, Epstein-Barr virus induced gene 1, Epstein-Barr virus induced G-protein coupled receptor, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI1, lymphocyte-specific G protein-coupled peptide receptor, MIP-3 beta receptor
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.