Human CCR7 APC-conjugated Antibody | R&D Systems FAB197A-025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR7 APC-conjugated Antibody

catalog :

FAB197A-025

quantity :

25 Tests (also 100 Tests)

price :

159 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

150503

reactivity :

human, rhesus macaque

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 24

Reference
Kamsom C, Edwards S, Thaosing J, Papalee S, Pientong C, Kurosu T, et al. Altered neutrophil responses to dengue virus serotype three: delayed apoptosis is regulated by stabilisation of Mcl-1. Sci Rep. 2024;14:18414 pubmed publisher
Vestre K, Persiconi I, Borg Distefano M, Mensali N, Guadagno N, Bretou M, et al. Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton. J Cell Sci. 2021;134: pubmed publisher
Artinger M, Matti C, Gerken O, Veldkamp C, Legler D. A Versatile Toolkit for Semi-Automated Production of Fluorescent Chemokines to Study CCR7 Expression and Functions. Int J Mol Sci. 2021;22: pubmed publisher
Brudno J, Lam N, Vanasse D, Shen Y, Rose J, Rossi J, et al. Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma. Nat Med. 2020;26:270-280 pubmed publisher
Laufer J, Hauser M, Kindinger I, Purvanov V, Pauli A, Legler D. Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation. Cell Rep. 2019;29:995-1009.e6 pubmed publisher
J xf8 rgensen A, Larsen O, Uetz von Allmen E, L xfc ckmann M, Legler D, Frimurer T, et al. Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7. Front Immunol. 2019;10:2156 pubmed publisher
Jakobs B, Spannagel L, Purvanov V, Uetz von Allmen E, Matti C, Legler D. Engineering of Nanobodies Recognizing the Human Chemokine Receptor CCR7. Int J Mol Sci. 2019;20: pubmed publisher
Laufer J, Kindinger I, Artinger M, Pauli A, Legler D. CCR7 Is Recruited to the Immunological Synapse, Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP70. Front Immunol. 2018;9:3115 pubmed publisher
Wallner S, Orso E, Grandl M, Konovalova T, Liebisch G, Schmitz G. Phosphatidylcholine and phosphatidylethanolamine plasmalogens in lipid loaded human macrophages. PLoS ONE. 2018;13:e0205706 pubmed publisher
Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
Uetz von Allmen E, Rippl A, Farhan H, Legler D. A unique signal sequence of the chemokine receptor CCR7 promotes package into COPII vesicles for efficient receptor trafficking. J Leukoc Biol. 2018;104:375-389 pubmed publisher
van der Wagen L, Te Boome L, Schiffler M, Nijhof I, Schoordijk M, van Dorp S, et al. Prospective evaluation of sequential treatment of sclerotic chronic graft versus host disease with rituximab and nilotinib. Bone Marrow Transplant. 2018;53:1255-1262 pubmed publisher
Darboe A, Danso E, Clarke E, Umesi A, Touray E, Wegmüller R, et al. Enhancement of cytokine-driven NK cell IFN-γ production after vaccination of HCMV infected Africans. Eur J Immunol. 2017;47:1040-1050 pubmed publisher
Portero Sainz I, GÃ³mez GarcÃa de Soria V, Cuesta Mateos C, FernÃ¡ndez Arandojo C, Vega Piris L, Royg M, et al. A high migratory capacity of donor T-cells in response to the lymph node homing receptor CCR7 increases the incidence and severity of GvHD. Bone Marrow Transplant. 2017;52:745-752 pubmed publisher
Iyer S, Gangadhara S, Victor B, Gomez R, Basu R, Hong J, et al. Codelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques. J Immunol. 2015;195:994-1005 pubmed publisher
Westera L, van Hoeven V, Drylewicz J, Spierenburg G, van Velzen J, de Boer R, et al. Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover. Aging Cell. 2015;14:219-27 pubmed publisher
Bergamaschi C, Kulkarni V, Rosati M, Alicea C, Jalah R, Chen S, et al. Intramuscular delivery of heterodimeric IL-15 DNA in macaques produces systemic levels of bioactive cytokine inducing proliferation of NK and T cells. Gene Ther. 2015;22:76-86 pubmed publisher
Le Brocq M, Fraser A, Cotton G, Woznica K, McCulloch C, Hewitt K, et al. Chemokines as novel and versatile reagents for flow cytometry and cell sorting. J Immunol. 2014;192:6120-6130 pubmed publisher
Jagannathan P, Eccles James I, Bowen K, Nankya F, Auma A, Wamala S, et al. IFN?/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children. PLoS Pathog. 2014;10:e1003864 pubmed publisher
Dintwe O, Day C, Smit E, Nemes E, Gray C, Tameris M, et al. Heterologous vaccination against human tuberculosis modulates antigen-specific CD4+ T-cell function. Eur J Immunol. 2013;43:2409-20 pubmed publisher
Beziat V, Nguyen S, Exley M, Achour A, Simon T, Chevallier P, et al. Shaping of iNKT cell repertoire after unrelated cord blood transplantation. Clin Immunol. 2010;135:364-73 pubmed publisher
Bayry J, Triebel F, Kaveri S, Tough D. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J Immunol. 2007;178:4184-93 pubmed
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product information

master code :

FAB197A

SKU :

FAB197A-025

product name :

Human CCR7 APC-conjugated Antibody

unit size :

25 Tests (also 100 Tests)

description :

The Human CCR7 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCR7. This antibody reacts with human,primate - macaca mulatta (rhesus macaque). The Human CCR7 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunocytochemistry.

target :

CCR7

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

150503

conjugate :

Allophycocyanin

host :

Mouse

immunogen :

Human CCR7 transfectants, Met1-Pro378, Accession # AAA58615

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human CCR7.

gene symbol :

CCR7

top caption :

Detection of CCR7 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

accessionNumbers :

AAA58615

applications :

Flow Cytometry,Western Blot,Immunocytochemistry

extended description :

Clone 150503 was used by HLDA to establish CD designation

USD :

159 USD

product details :

Clone 150503 was used by HLDA to establish CD designation

alt names :

BLR2, BLR2C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR7, CCR-7, CD197, CD197 antigen, CDw197, CDw197CC chemokine receptor 7, chemokine (C-C motif) receptor 7, CMKBR7, CMKBR7chemokine (C-C) receptor 7, EBI1, EBI1EBV-induced G protein-coupled receptor 1, EBV-induced G-protein coupled receptor 1, Epstein-Barr virus induced gene 1, Epstein-Barr virus induced G-protein coupled receptor, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI1, lymphocyte-specific G protein-coupled peptide receptor, MIP-3 beta receptor

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage