product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse IL-12 R▀2 APC-conjugated Antibody
catalog :
FAB1959A-100
quantity :
100 Tests (also 25 Tests)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
305719
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 7
Reference
Pandey S, Bender M, McPherson A, Phelps C, Sanchez L, Rana M, et al. Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. Cell Host Microbe. 2022;30:1003-1019.e10 pubmed publisher
Singh A, Subhi Y, Krogh Nielsen M, Falk M, Matzen S, Sellebjerg F, et al. Systemic frequencies of T helper 1 and T helper 17 cells in patients with age-related macular degeneration: A case-control study. Sci Rep. 2017;7:605 pubmed publisher
Dendrou C, Cortes A, Shipman L, Evans H, Attfield K, Jostins L, et al. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. Sci Transl Med. 2016;8:363ra149 pubmed
Nguyen T, Frye J, Zbesko J, Stepanovic K, Hayes M, Urzua A, et al. Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. Acta Neuropathol Commun. 2016;4:100 pubmed publisher
Gokhale M, Vainstein V, Tom J, Thomas S, Lawrence C, Gluzman Poltorak Z, et al. Single low-dose rHuIL-12 safely triggers multilineage hematopoietic and immune-mediated effects. Exp Hematol Oncol. 2014;3:11 pubmed publisher
Liu Y, Xu Y, Sun J, Ma A, Zhang F, Xia S, et al. AKT hyperactivation confers a Th1 phenotype in thymic Treg cells deficient in TGF-? receptor II signaling. Eur J Immunol. 2014;44:521-32 pubmed publisher
Liao W, Lin J, Wang L, Li P, Leonard W. Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat Immunol. 2011;12:551-9 pubmed publisher
product information
master code :
FAB1959A
SKU :
FAB1959A-100
product name :
Human/Mouse IL-12 R▀2 APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human/Mouse IL-12 Rß2 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to IL-12 R beta 2. This antibody reacts with human,mouse. The Human/Mouse IL-12 Rß2 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
IL-12 R beta 2
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
305719
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human IL-12 R▀2, Cys28-Asn622, Accession # Q99665
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human and mouse IL-12 R▀2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human IL-1 R▀1 is observed.
gene symbol :
IL12RB2
top caption :
Detection of IL-12 Rss2 antibody in Human TH1 cells antibody by Flow Cytometry.
accessionNumbers :
Q99665
applications :
Flow Cytometry
USD :
439 USD
alt names :
IL-12 receptor beta 2, IL-12 receptor subunit beta-2, IL12R beta 2, IL-12R subunit beta-2, IL12RB2, IL-12RB2, IL-12R-beta-2, interleukin 12 receptor, beta 2, interleukin-12 receptor beta-2 chain, interleukin-12 receptor subunit beta-2
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.