Human CXCR5 PE-conjugated Antibody | R&D Systems FAB190P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCR5 PE-conjugated Antibody

catalog :

FAB190P

quantity :

25 Tests (also 100 Tests)

price :

119 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

51505

reactivity :

human

application :

flow cytometry

citations: 21

Reference
Cunill V, Clemente A, Lanio N, Barceló C, Andreu V, Pons J, et al. Follicular T Cells from smB- Common Variable Immunodeficiency Patients Are Skewed Toward a Th1 Phenotype. Front Immunol. 2017;8:174 pubmed publisher
Shankar V, Hori H, Kihira K, Lei Q, Toyoda H, Iwamoto S, et al. Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in neuroblastoma cell lines. PLoS ONE. 2015;10:e0120069 pubmed publisher
Martinez Martin N, Viejo Borbolla A, MartÃn R, Blanco S, Benovic J, Thelen M, et al. Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization. Nat Commun. 2015;6:6163 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Lehmann D, Spanholtz J, Sturtzel C, Tordoir M, Schlechta B, Groenewegen D, et al. IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential. PLoS ONE. 2014;9:e87131 pubmed publisher
Badr G, Lefevre E, Mohany M. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE. 2011;6:e23741 pubmed publisher
Barbosa R, Silva S, Silva S, Melo A, Pedro E, Barbosa M, et al. Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation. PLoS ONE. 2011;6:e22848 pubmed publisher
Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, et al. Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. Clin Exp Immunol. 2011;163:215-24 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Ehlin Henriksson B, Liang W, Cagigi A, Mowafi F, Klein G, Nilsson A. Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection. Immunology. 2009;127:549-57 pubmed publisher
Panse J, Friedrichs K, Marx A, Hildebrandt Y, Luetkens T, Barrels K, et al. Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients. Br J Cancer. 2008;99:930-8 pubmed publisher
Cagigi A, Mowafi F, Phuong Dang L, Tenner Racz K, Atlas A, Grutzmeier S, et al. Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection. Blood. 2008;112:4401-10 pubmed publisher
Moir S, Ho J, Malaspina A, Wang W, DiPoto A, O Shea M, et al. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med. 2008;205:1797-805 pubmed publisher
Maru S, Holloway K, Flynn G, Lancashire C, Loughlin A, Male D, et al. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. J Neuroimmunol. 2008;199:35-45 pubmed publisher
Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, et al. CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1. Cancer Res. 2008;68:790-9 pubmed publisher
Badr G, Borhis G, Lefevre E, Chaoul N, Deshayes F, Dessirier V, et al. BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells. Blood. 2008;111:2744-54 pubmed publisher
Bürkle A, Niedermeier M, Schmitt Gräff A, Wierda W, Keating M, Burger J. Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia. Blood. 2007;110:3316-25 pubmed
Ettinger R, Sims G, Robbins R, Withers D, Fischer R, Grammer A, et al. IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J Immunol. 2007;178:2872-82 pubmed
Muller A, Sonkoly E, Eulert C, Gerber P, Kubitza R, Schirlau K, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer. 2006;118:2147-57 pubmed
Piovan E, Tosello V, Indraccolo S, Cabrelle A, Baesso I, Trentin L, et al. Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation. Blood. 2005;105:931-9 pubmed
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle M, et al. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J Leukoc Biol. 2003;73:584-90 pubmed

product information

brand :

R&D Systems

master code :

FAB190P

SKU :

FAB190P-025

product name :

Human CXCR5 PE-conjugated Antibody

description :

The Human CXCR5 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CXCR5. This antibody reacts with human. The Human CXCR5 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

CXCR5

category :

Primary Antibodies

unit size :

25 Tests (also 100 Tests)

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

51505

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CXCR5, Met1-Phe372, Accession # P32302

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Stains human CXCR5 transfectants but not the parental cell lines in flow cytometry. Does not cross-react with human CXCR2, CXCR3, or CXCR4 transfectants.

gene symbol :

CXCR5

catalog number base :

FAB190P

accessionNumbers :

P32302

applications :

Flow Cytometry

extended description :

Clone 51505 was used by HLDA to establish CD designation

2020 USD :

119

2021 USD :

119 USD

product details :

Clone 51505 was used by HLDA to establish CD designation

alt names :

BLR1, BLR1MDR-15, Burkitt lymphoma receptor 1, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5), Burkitt lymphoma receptor 1, GTP-binding protein, CD185, CD185 antigen, chemokine (C-X-C motif) receptor 5, C-X-C chemokine receptor type 5, CXCR5, CXC-R5, MDR15CXCR-5, MGC117347, Monocyte-derived receptor 15

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.