Human Dectin-1/CLEC7A PE-conjugated Antibody | R&D Systems FAB1859P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Dectin-1/CLEC7A PE-conjugated Antibody

catalog :

FAB1859P

quantity :

25 Tests

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

259931

reactivity :

human

application :

flow cytometry

citations: 9

Reference
Kotthoff P, Heine A, Held S, Brossart P. Dexamethasone induced inhibition of Dectin-1 activation of antigen presenting cells is mediated via STAT-3 and NF-κB signaling pathways. Sci Rep. 2017;7:4522 pubmed publisher
Fischer M, Müller J, Spies Weisshart B, Grafe C, Kurzai O, Hünniger K, et al. Isoform localization of Dectin-1 regulates the signaling quality of anti-fungal immunity. Eur J Immunol. 2017;47:848-859 pubmed publisher
. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking ?-glucans. PLoS ONE. 2015;10:e0119244 pubmed publisher
Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M. Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system. PLoS ONE. 2013;8:e82734 pubmed publisher
Cardone M, Ikeda K, Varano B, Belardelli F, Millefiorini E, Gessani S, et al. Opposite regulatory effects of IFN-? and IL-3 on C-type lectin receptors, antigen uptake, and phagocytosis in human macrophages. J Leukoc Biol. 2014;95:161-8 pubmed publisher
Li D, Dong B, Tong Z, Wang Q, Liu W, Wang Y, et al. MBL-mediated opsonophagocytosis of Candida albicans by human neutrophils is coupled with intracellular Dectin-1-triggered ROS production. PLoS ONE. 2012;7:e50589 pubmed publisher
Khoo A, Chai L, Koenen H, Oosting M, Steinmeyer A, Zuegel U, et al. Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production. Cytokine. 2011;55:294-300 pubmed publisher
Llinàs L, Lázaro A, de Salort J, Matesanz Isabel J, Sintes J, Engel P. Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. Immunol Lett. 2011;134:113-21 pubmed publisher
Cunha C, Di Ianni M, Bozza S, Giovannini G, Zagarella S, Zelante T, et al. Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity. Blood. 2010;116:5394-402 pubmed publisher

product information

brand :

R&D Systems

master code :

FAB1859P

SKU :

FAB1859P-025

product name :

Human Dectin-1/CLEC7A PE-conjugated Antibody

description :

The Human Dectin-1/CLEC7A PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Dectin-1/CLEC7A. This antibody reacts with human. The Human Dectin-1/CLEC7A PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

Dectin-1/CLEC7A

category :

Primary Antibodies

unit size :

25 Tests

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

259931

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Dectin-1/CLEC7A, Thr66-Met201, Accession # NP_072092

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Dectin-1/CLEC7A in direct ELISAs. In directs ELISAs, less than 10% cross-reactivity with recombinant human (rh) DLEC and no cross-reactivity with recombinant mouse Dectin-1 or rhDectin-2 is observed.

gene symbol :

CLEC7A

catalog number base :

FAB1859P

accessionNumbers :

NP_072092

applications :

Flow Cytometry

extended description :

Clone 259931 was used by HLDA to establish CD designation

2020 USD :

149

2021 USD :

149 USD

product details :

Clone 259931 was used by HLDA to establish CD designation

alt names :

Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.