Human Dectin-1/CLEC7A PE-conjugated Antibody | R&D Systems FAB1859P-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Dectin-1/CLEC7A PE-conjugated Antibody

catalog :

FAB1859P-100

quantity :

100 Tests (also 25 Tests)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

259931

reactivity :

human

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 13

Reference
Xie X, He J, Wang Q, Liu Y, Chen W, Shi K. FPR2 participates in epithelial ovarian cancer (EOC) progression through RhoA-mediated M2 macrophage polarization. J Ovarian Res. 2021;14:177 pubmed publisher
Kotthoff P, Heine A, Held S, Brossart P. Dexamethasone induced inhibition of Dectin-1 activation of antigen presenting cells is mediated via STAT-3 and NF-κB signaling pathways. Sci Rep. 2017;7:4522 pubmed publisher
Fischer M, Müller J, Spies Weisshart B, Grafe C, Kurzai O, Hünniger K, et al. Isoform localization of Dectin-1 regulates the signaling quality of anti-fungal immunity. Eur J Immunol. 2017;47:848-859 pubmed publisher
Fischer M, Spies Weisshart B, Schrenk K, Gruhn B, Wittig S, Glaser A, et al. Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia. PLoS ONE. 2016;11:e0150632 pubmed publisher
Clark G, Kupresanin F, Fromm P, Ju X, Muusers L, Silveira P, et al. New insights into the phenotype of human dendritic cell populations. Clin Transl Immunology. 2016;5:e61 pubmed publisher
. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking ?-glucans. PLoS ONE. 2015;10:e0119244 pubmed publisher
Dong B, Li D, Li R, Chen S, Liu W, Liu W, et al. A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking Î²-glucans. PLoS ONE. 2014;9:e114113 pubmed publisher
Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M. Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system. PLoS ONE. 2013;8:e82734 pubmed publisher
Cardone M, Ikeda K, Varano B, Belardelli F, Millefiorini E, Gessani S, et al. Opposite regulatory effects of IFN-? and IL-3 on C-type lectin receptors, antigen uptake, and phagocytosis in human macrophages. J Leukoc Biol. 2014;95:161-8 pubmed publisher
Li D, Dong B, Tong Z, Wang Q, Liu W, Wang Y, et al. MBL-mediated opsonophagocytosis of Candida albicans by human neutrophils is coupled with intracellular Dectin-1-triggered ROS production. PLoS ONE. 2012;7:e50589 pubmed publisher
Khoo A, Chai L, Koenen H, Oosting M, Steinmeyer A, Zuegel U, et al. Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production. Cytokine. 2011;55:294-300 pubmed publisher
Llinàs L, Lázaro A, de Salort J, Matesanz Isabel J, Sintes J, Engel P. Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. Immunol Lett. 2011;134:113-21 pubmed publisher
Cunha C, Di Ianni M, Bozza S, Giovannini G, Zagarella S, Zelante T, et al. Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity. Blood. 2010;116:5394-402 pubmed publisher

product information

master code :

FAB1859P

SKU :

FAB1859P-100

product name :

Human Dectin-1/CLEC7A PE-conjugated Antibody

unit size :

100 Tests (also 25 Tests)

description :

The Human Dectin-1/CLEC7A PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Dectin-1/CLEC7A. This antibody reacts with human. The Human Dectin-1/CLEC7A PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Neutralization.

target :

Dectin-1/CLEC7A

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

259931

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Dectin-1/CLEC7A, Thr66-Met201, Accession # NP_072092

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Dectin-1/CLEC7A in direct ELISAs. In directs ELISAs, less than 10% cross-reactivity with recombinant human (rh) DLEC and no cross-reactivity with recombinant mouse Dectin-1 or rhDectin-2 is observed.

gene symbol :

CLEC7A

top caption :

Detection of Dectin-1/CLEC7A antibody in Human Blood Monocytes antibody by Flow Cytometry.

accessionNumbers :

NP_072092

applications :

Flow Cytometry,Neutralization

extended description :

Clone 259931 was used by HLDA to establish CD designation

USD :

369 USD

product details :

Clone 259931 was used by HLDA to establish CD designation

alt names :

Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage