product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Dectin-1/CLEC7A APC-conjugated Antibody
catalog :
FAB1859A-100
quantity :
100 Tests (also 25 Tests)
price :
419 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
259931
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 7
Reference
Tam J, Reedy J, Lukason D, Kuna S, Acharya M, Khan N, et al. Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans. J Immunol. 2019;202:3256-3266 pubmed publisher
Gresnigt M, Cunha C, Jaeger M, Gonçalves S, Malireddi R, Ammerdorffer A, et al. Genetic deficiency of NOD2 confers resistance to invasive aspergillosis. Nat Commun. 2018;9:2636 pubmed publisher
Gresnigt M, Jaeger M, Subbarao Malireddi R, Raşid O, Jouvion G, Fitting C, et al. The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression. Front Immunol. 2017;8:1777 pubmed publisher
van Haren S, Dowling D, Foppen W, Christensen D, Andersen P, Reed S, et al. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016;197:4413-4424 pubmed
Camargo J, Bhimji A, Kumar D, Kaul R, Pavan R, Schuh A, et al. Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis. PLoS ONE. 2015;10:e0123171 pubmed publisher
Kleinnijenhuis J, Quintin J, Preijers F, Benn C, Joosten L, Jacobs C, et al. Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity. J Innate Immun. 2014;6:152-8 pubmed publisher
Kleinnijenhuis J, Quintin J, Preijers F, Joosten L, Ifrim D, Saeed S, et al. Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes. Proc Natl Acad Sci U S A. 2012;109:17537-42 pubmed publisher
product information
master code :
FAB1859A
SKU :
FAB1859A-100
product name :
Human Dectin-1/CLEC7A APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human Dectin-1/CLEC7A APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Dectin-1/CLEC7A. This antibody reacts with human. The Human Dectin-1/CLEC7A APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
Dectin-1/CLEC7A
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
259931
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Dectin-1/CLEC7A, Thr66-Met201, Accession # NP_072092
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Dectin-1/CLEC7A in direct ELISAs. In directs ELISAs, less than 10% cross-reactivity with recombinant human (rh) DLEC and no cross-reactivity with recombinant mouse Dectin-1 or rhDectin-2 is observed.
gene symbol :
CLEC7A
top caption :
Detection of Dectin-1/CLEC7A antibody in Human Blood Monocytes antibody by Flow Cytometry.
accessionNumbers :
NP_072092
applications :
Flow Cytometry
extended description :
Clone 259931 was used by HLDA to establish CD designation
USD :
419 USD
product details :
Clone 259931 was used by HLDA to establish CD designation
alt names :
Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.