product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat CCR5 APC-conjugated Antibody
catalog :
FAB1802A-025
quantity :
25 Tests (also 100 Tests)
price :
149 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
CTC5
reactivity :
human, mouse, rat
application :
immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 10
Reference
Jiao X, Wang M, Zhang Z, Li Z, Ni D, Ashton A, et al. Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy. Breast Cancer Res. 2021;23:11 pubmed publisher
Laufer J, Hauser M, Kindinger I, Purvanov V, Pauli A, Legler D. Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation. Cell Rep. 2019;29:995-1009.e6 pubmed publisher
Jiao X, Velasco Velázquez M, Wang M, Li Z, Rui H, Peck A, et al. CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion. Cancer Res. 2018;78:1657-1671 pubmed publisher
Godinho Santos A, Hance A, Gonçalves J, Mammano F. CIB1 and CIB2 are HIV-1 helper factors involved in viral entry. Sci Rep. 2016;6:30927 pubmed publisher
Sicoli D, Jiao X, Ju X, Velasco Velázquez M, Ertel A, Addya S, et al. CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines. Cancer Res. 2014;74:7103-14 pubmed publisher
Baturcam E, Abubaker J, Tiss A, Abu Farha M, Khadir A, Al Ghimlas F, et al. Physical exercise reduces the expression of RANTES and its CCR5 receptor in the adipose tissue of obese humans. Mediators Inflamm. 2014;2014:627150 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Velasco Velázquez M, Jiao X, de la Fuente M, Pestell T, Ertel A, Lisanti M, et al. CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Res. 2012;72:3839-50 pubmed publisher
Prendergast A, Prado J, Kang Y, Chen F, Riddell L, Luzzi G, et al. HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells. AIDS. 2010;24:491-502 pubmed publisher
Bayry J, Triebel F, Kaveri S, Tough D. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J Immunol. 2007;178:4184-93 pubmed
product information
brand :
R&D Systems
master code :
FAB1802A
SKU :
FAB1802A-025
product name :
Human/Mouse/Rat CCR5 APC-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
seo description :
The Human/Mouse/Rat CCR5 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCR5. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat CCR5 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry.
target :
CCR5
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
CTC5
conjugate :
Allophycocyanin
dilution :
Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
CHO Chinese hamster ovary cell line transfected with human CCR5
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human CCR5 in Western blots. For additional information regarding epitope specificity for this antibody and other R D Systems anti-human CCR5 antibodies, see Reference 1.
gene symbol :
CCR5
top caption :
Detection of CCR5 antibody in Human PBMCs antibody by Flow Cytometry.
applications :
Flow Cytometry,Immunocytochemistry
USD :
149 USD
alt names :
C-C CKR-5, C-C motif chemokine receptor 5 A159A, CCCKR5, CC-CKR-5FLJ78003, CCR5, CCR-5, CD195, CD195 antigen, chemokine (C-C motif) receptor 5, chemokine receptor CCR5, chemr13, CKR5, CKR-5, HIV-1 fusion coreceptor, IDDM22CMKBR5C-C chemokine receptor type 5
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.