product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Dectin-1/CLEC7A PE-conjugated Antibody
catalog :
FAB17561P
quantity :
100 Tests
price :
359 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
218820
reactivity :
mouse
application :
immunocytochemistry, neutralization, flow cytometry
more info or order :
citations: 5
Reference
Loh J, Xu S, Huo J, Kim S, Wang Y, Lam K. Dok3-protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity. J Clin Invest. 2019;129:2717-2729 pubmed publisher
Dong B, Tong Z, Li R, Chen S, Liu W, Liu W, et al. Transformation of Fonsecaea pedrosoi into sclerotic cells links to the refractoriness of experimental chromoblastomycosis in BALB/c mice via a mechanism involving a chitin-induced impairment of IFN-γ production. PLoS Negl Trop Dis. 2018;12:e0006237 pubmed publisher
. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking ?-glucans. PLoS ONE. 2015;10:e0119244 pubmed publisher
Dong B, Li D, Li R, Chen S, Liu W, Liu W, et al. A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans. PLoS ONE. 2014;9:e114113 pubmed publisher
Xu S, Huo J, Gunawan M, Su I, Lam K. Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells. J Biol Chem. 2009;284:22005-11 pubmed publisher
product information
master code :
FAB17561P
SKU :
FAB17561P
product name :
Mouse Dectin-1/CLEC7A PE-conjugated Antibody
unit size :
100 Tests
description :
The Mouse Dectin-1/CLEC7A PE-conjugated Antibody from R&D Systems is a rat monoclonal antibody to Dectin-1/CLEC7A. This antibody reacts with mouse. The Mouse Dectin-1/CLEC7A PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunocytochemistry.
target :
Dectin-1/CLEC7A
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
218820
conjugate :
Phycoerythrin
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Dectin-1/CLEC7A, Phe69-Leu244, Accession # Q6QLQ4
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse Dectin-1/CLEC7A in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Dectin-1 is observed and no cross-reactivity with recombinant mouse Dectin-2 or rhDLEC is observed.
gene symbol :
CLEC7A
top caption :
Detection of Dectin-1/CLEC7A antibody in Mouse Blood Monocytes antibody by Flow Cytometry.
accessionNumbers :
Q6QLQ4
applications :
Flow Cytometry,Neutralization,Immunocytochemistry
USD :
359 USD
alt names :
Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.