Human CXCR4 PE-conjugated Antibody | R&D Systems FAB173P-025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCR4 PE-conjugated Antibody

catalog :

FAB173P-025

quantity :

25 Tests (also 100 Tests)

price :

139 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

44717

reactivity :

human

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 14

Reference
Mattis K, Krentz N, Metzendorf C, Abaitua F, Spigelman A, Sun H, et al. Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression. Diabetologia. 2023;66:674-694 pubmed publisher
Sadeghi L, Arvidsson G, Merrien M, M Wasik A, Görgens A, Smith C, et al. Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells. Cancers (Basel). 2020;12: pubmed publisher
Schober T, Magg T, Laschinger M, Rohlfs M, Linhares N, Puchalka J, et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun. 2017;8:14209 pubmed publisher
Peng S, Zhang X, Paul D, Kays L, Ye M, Vaillancourt P, et al. Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies. PLoS ONE. 2016;11:e0150585 pubmed publisher
Buckner C, Moir S, Kardava L, Ho J, Santich B, Kim L, et al. CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation. J Allergy Clin Immunol. 2014;133:1676-85.e5 pubmed publisher
Liu C, Pham K, Luo D, Reynolds B, Hothi P, Foltz G, et al. Expression and functional heterogeneity of chemokine receptors CXCR4 and CXCR7 in primary patient-derived glioblastoma cells. PLoS ONE. 2013;8:e59750 pubmed publisher
Gillespie E, Raychaudhuri N, Papageorgiou K, Atkins S, Lu Y, Charara L, et al. Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-?B. Invest Ophthalmol Vis Sci. 2012;53:7746-53 pubmed publisher
Badr G, Lefevre E, Mohany M. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE. 2011;6:e23741 pubmed publisher
Raposo R, Trudgian D, Thomas B, van Wilgenburg B, Cowley S, James W. Protein kinase C and NF-?B-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection. J Immunol. 2011;187:748-59 pubmed publisher
Singh H, Figliola M, Dawson M, Huls H, Olivares S, Switzer K, et al. Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies. Cancer Res. 2011;71:3516-27 pubmed publisher
Scala S, Giuliano P, Ascierto P, Ierano C, Franco R, Napolitano M, et al. Human melanoma metastases express functional CXCR4. Clin Cancer Res. 2006;12:2427-33 pubmed
Hatse S, Princen K, Vermeire K, Gerlach L, Rosenkilde M, Schwartz T, et al. Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry. FEBS Lett. 2003;546:300-6 pubmed
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle M, et al. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J Leukoc Biol. 2003;73:584-90 pubmed
de Lavareille A, Roufosse F, Schandene L, Stordeur P, Cogan E, Goldman M. Clonal Th2 cells associated with chronic hypereosinophilia: TARC-induced CCR4 down-regulation in vivo. Eur J Immunol. 2001;31:1037-46 pubmed

product information

master code :

FAB173P

SKU :

FAB173P-025

product name :

Human CXCR4 PE-conjugated Antibody

unit size :

25 Tests (also 100 Tests)

description :

The Human CXCR4 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CXCR4. This antibody reacts with human. The Human CXCR4 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

CXCR4

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

44717

conjugate :

Phycoerythrin

host :

Mouse

immunogen :

Mouse 3T3 cells transfected with human CXCR4

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Reacts specifically with human and non-human cells expressing human CXCR4 (fusin) as detected by flow cytometry. It will also react with cells expressing feline CXCR4 but not rat CXCR4. This antibody does not cross-react with other chemokine receptors.

gene symbol :

CXCR4

top caption :

Detection of CXCR4 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

applications :

Flow Cytometry

USD :

139 USD

alt names :

CD184, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C motif), receptor 4 (fusin), C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, D2S201E, D2S201ESDF-1 receptor, FB22, Fusin, HM89, HM89NPYRL, HSY3RR, LAP3, LAP-3, LCR1, LESTR, LESTRCD184 antigen, Leukocyte-derived seven transmembrane domain receptor, leukocyte-derived seven-transmembrane-domain receptor, lipopolysaccharide-associated protein 3, neuropeptide Y receptor Y3, NPY3R, NPY3RWHIM, NPYR, NPYRL, NPYY3R, pCXCR4, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, Stromal cell-derived factor 1 receptor, WHIMS

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage