product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse TREM2 PE-conjugated Antibody
catalog :
FAB17291P
quantity :
100 Tests
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
237920
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 9
Reference
Zhang J, Chang J, Chen V, Beg M, Huang W, Vick L, et al. Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway. bioRxiv. 2024;: pubmed publisher
Fulton S, Bendl J, Gameiro Ros I, Fullard J, Al Kachak A, Lepack A, et al. ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex. bioRxiv. 2023;: pubmed publisher
Wang H, Yang F, Yang C, Liu Y, Ko P, Li C, et al. Surface TREM2 on circulating M-MDSCs as a novel prognostic factor for adults with treatment-naïve diffuse large B-cell lymphoma. Exp Hematol Oncol. 2023;12:35 pubmed publisher
Li S, Yu J, Huber A, Kryczek I, Wang Z, Jiang L, et al. Metabolism drives macrophage heterogeneity in the tumor microenvironment. Cell Rep. 2022;39:110609 pubmed publisher
McAlpine C, Park J, Griciuc A, Kim E, Choi S, Iwamoto Y, et al. Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature. 2021;595:701-706 pubmed publisher
Hu M, Lin Y, Men X, Wang S, Sun X, Zhu Q, et al. High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke. J Neuroinflammation. 2021;18:90 pubmed publisher
Vagima Y, Gur D, Erez N, Achdout H, Aftalion M, Levy Y, et al. Influenza virus infection augments susceptibility to respiratory Yersinia pestis exposure and impacts the efficacy of antiplague antibiotic treatments. Sci Rep. 2020;10:19116 pubmed publisher
B xe9 chade C, D Andrea I, Etienne F, Verdonk F, Moutkine I, Banas S, et al. The serotonin 2B receptor is required in neonatal microglia to limit neuroinflammation and sickness behavior in adulthood. Glia. 2021;69:638-654 pubmed publisher
Clark G, Kupresanin F, Fromm P, Ju X, Muusers L, Silveira P, et al. New insights into the phenotype of human dendritic cell populations. Clin Transl Immunology. 2016;5:e61 pubmed publisher
product information
master code :
FAB17291P
SKU :
FAB17291P
product name :
Human/Mouse TREM2 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human/Mouse TREM2 PE-conjugated Antibody from R&D Systems is a rat monoclonal antibody to TREM2. This antibody reacts with human,mouse,transgenic mouse. The Human/Mouse TREM2 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
TREM2
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
237920
conjugate :
Phycoerythrin
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse TREM-2, extracellular domain, Accession # Q99NH8
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects human and mouse TREM-2 in direct ELISAs and Western blots. Stains TREM-2 transfectants but not TREM-1 transfectants.
gene symbol :
TREM2
top caption :
Detection of TREM-2 antibody in RAW 264.7 Mouse Cell Line antibody by Flow Cytometry.
accessionNumbers :
Q99NH8
applications :
Flow Cytometry
USD :
459 USD
alt names :
PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c, TREM-2triggering receptor expressed on myeloid cells 2a, Triggering receptor expressed on monocytes 2, triggering receptor expressed on myeloid cells 2
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied. Protect from light.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.