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company name :
R&D Systems
product type :
antibody
product name :
Human CXCR4 Fluorescein-conjugated Antibody
catalog :
FAB170F-025
quantity :
25 Tests (also 100 Tests)
price :
129 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
12G5
reactivity :
human
application :
flow cytometry
more info or order :
citations: 12
Reference
Amniai L, Ple C, Barrier M, de Nadai P, Marquillies P, Vorng H, et al. Natural Killer Cells from Allergic Donors Are Defective in Their Response to CCL18 Chemokine. Int J Mol Sci. 2021;22: pubmed publisher
Wang M, Feng R, Zhang J, Xu L, Feng F, Wang C, et al. Dysregulated megakaryocyte distribution associated with nestin+ mesenchymal stem cells in immune thrombocytopenia. Blood Adv. 2019;3:1416-1428 pubmed publisher
Maghazachi A, Sand K, Al Jaderi Z. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity. Front Immunol. 2016;7:437 pubmed
Ma N, Pang H, Shen W, Zhang F, Cui Z, Wang J, et al. Downregulation of CXCR4 by SDF-KDEL in SBC-5 cells inhibits their migration in vitro and organ metastasis in vivo. Int J Mol Med. 2015;35:425-32 pubmed publisher
Li Q, Zhang A, Tao C, Li X, Jin P. The role of SDF-1-CXCR4/CXCR7 axis in biological behaviors of adipose tissue-derived mesenchymal stem cells in vitro. Biochem Biophys Res Commun. 2013;441:675-80 pubmed publisher
Pandya A, Al Jaderi Z, Høglund R, Holmøy T, Harbo H, Norgauer J, et al. Identification of human NK17/NK1 cells. PLoS ONE. 2011;6:e26780 pubmed publisher
Bosco M, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, et al. Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Blood. 2011;117:2625-39 pubmed publisher
Hajishengallis G, Wang M, Liang S, Triantafilou M, Triantafilou K. Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function. Proc Natl Acad Sci U S A. 2008;105:13532-7 pubmed publisher
Garcia G, Humbert M, Capel F, Rimaniol A, Escourrou P, Emilie D, et al. Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis. Allergy. 2007;62:170-7 pubmed
Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, et al. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells. Immunology. 2004;112:274-89 pubmed
Howard O, Dong H, Yang D, Raben N, Nagaraju K, Rosen A, et al. Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. J Exp Med. 2002;196:781-91 pubmed
Zamarchi R, Allavena P, Borsetti A, Stievano L, Tosello V, Marcato N, et al. Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes. Clin Exp Immunol. 2002;127:321-30 pubmed
product information
master code :
FAB170F
SKU :
FAB170F-025
product name :
Human CXCR4 Fluorescein-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Human CXCR4 Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CXCR4. This antibody reacts with human. The Human CXCR4 Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
CXCR4
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
12G5
conjugate :
Fluorescein
host :
Mouse
immunogen :
CP-MAC-infected SUP-T1 human T cell lymphoblastic lymphoma line, Accession # P61073
isotype :
IgG2a
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human CXCR4.
gene symbol :
CXCR4
top caption :
Detection of CXCR4 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
accessionNumbers :
P61073
applications :
Flow Cytometry
USD :
129 USD
alt names :
CD184, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C motif), receptor 4 (fusin), C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, D2S201E, D2S201ESDF-1 receptor, FB22, Fusin, HM89, HM89NPYRL, HSY3RR, LAP3, LAP-3, LCR1, LESTR, LESTRCD184 antigen, Leukocyte-derived seven transmembrane domain receptor, leukocyte-derived seven-transmembrane-domain receptor, lipopolysaccharide-associated protein 3, neuropeptide Y receptor Y3, NPY3R, NPY3RWHIM, NPYR, NPYRL, NPYY3R, pCXCR4, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, Stromal cell-derived factor 1 receptor, WHIMS
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.