product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human DC-SIGN/CD209 Fluorescein-conjugated Antibody
catalog :
FAB161F-100
quantity :
100 Tests (also 25 Tests)
price :
319 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
120507
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 11
Reference
Valdez H, Marín Franco J, Gorgojo J, Alvarez Hayes J, Balboa L, Fernandez Lahore M, et al. Human macrophage polarization shapes B. pertussis intracellular persistence. J Leukoc Biol. 2022;112:173-184 pubmed publisher
Nijmeijer B, Sarrami Forooshani R, Steba G, Schreurs R, Koekkoek S, Molenkamp R, et al. HIV-1 exposure and immune activation enhance sexual transmission of Hepatitis C virus by primary Langerhans cells. J Int AIDS Soc. 2019;22:e25268 pubmed publisher
Otsuka Y, Watanabe E, Shinya E, Okura S, Saeki H, Geijtenbeek T, et al. Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells. J Immunol. 2018;201:3006-3016 pubmed publisher
Sprokholt J, Heineke M, Kaptein T, van Hamme J, Geijtenbeek T. DCs facilitate B cell responses against microbial DNA via DC-SIGN. PLoS ONE. 2017;12:e0185580 pubmed publisher
Rodriguez Garcia M, Shen Z, Barr F, Boesch A, Ackerman M, Kappes J, et al. Dendritic cells from the human female reproductive tract rapidly capture and respond to HIV. Mucosal Immunol. 2017;10:531-544 pubmed publisher
van den Berg L, Cardinaud S, van der Aar A, Sprokholt J, de Jong M, Zijlstra Willems E, et al. Langerhans Cell-Dendritic Cell Cross-Talk via Langerin and Hyaluronic Acid Mediates Antigen Transfer and Cross-Presentation of HIV-1. J Immunol. 2015;195:1763-73 pubmed publisher
Li J, Xia Y, Liu T, Wang J, Dai W, Wang F, et al. Protective effects of astaxanthin on ConA-induced autoimmune hepatitis by the JNK/p-JNK pathway-mediated inhibition of autophagy and apoptosis. PLoS ONE. 2015;10:e0120440 pubmed publisher
Bakema J, Tuk C, van Vliet S, Bruijns S, Vos J, Letsiou S, et al. Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs. J Immunol. 2015;194:1856-66 pubmed publisher
McAulay K, Haque T, Urquhart G, Bellamy C, Guiretti D, Crawford D. Epitope specificity and clonality of EBV-specific CTLs used to treat posttransplant lymphoproliferative disease. J Immunol. 2009;182:3892-901 pubmed publisher
Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, et al. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc Natl Acad Sci U S A. 2004;101:16606-11 pubmed
Nguyen D, Hildreth J. Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages. Eur J Immunol. 2003;33:483-93 pubmed
product information
master code :
FAB161F
SKU :
FAB161F-100
product name :
Human DC-SIGN/CD209 Fluorescein-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human DC-SIGN/CD209 Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to DC-SIGN/CD209. This antibody reacts with human. The Human DC-SIGN/CD209 Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
DC-SIGN/CD209
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
120507
conjugate :
Fluorescein
host :
Mouse
immunogen :
NIH-3T3 mouse embryonic fibroblast cell line transfected with human DC-SIGN/CD209
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human DC-SIGN/CD209 on transfected NIH/3T3 cells and on monocyte derived dendritic cells. Does not react with parental mouse cells or irrelevant transfectants, such as human DC-SIGN2.
gene symbol :
CD209
top caption :
Detection of DC-SIGN/CD209 antibody in NIH-3T3 Mouse Cell Line Transfected with Human DC-SIGN/CD209 antibody by Flow Cytometry.
applications :
Flow Cytometry
extended description :
Clone 120507 was used by HLDA to establish CD designation
USD :
319 USD
product details :
Clone 120507 was used by HLDA to establish CD designation
alt names :
CD209, CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin, CD209 molecule, CDSIGNHIV gpl20-binding protein, CLEC4L, CLEC4LC-type lectin domain family 4 member L, DCSIGN, DC-SIGN1, DC-SIGN1C-type lectin domain family 4, member L, DC-SIGNMGC129965, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.