product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human DC-SIGN/CD209 APC-conjugated Antibody
catalog :
FAB161A-100
quantity :
100 Tests (also 25 Tests)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
120507
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 7
Reference
Zhang L, Lepenies B, Nakamae S, Young B, Santos R, Raffatellu M, et al. The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN. MBio. 2022;13:e0273322 pubmed publisher
Zapatero Belinchón F, Dietzel E, Dolnik O, Döhner K, Costa R, Hertel B, et al. Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors. Viruses. 2019;11: pubmed publisher
Otsuka Y, Watanabe E, Shinya E, Okura S, Saeki H, Geijtenbeek T, et al. Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells. J Immunol. 2018;201:3006-3016 pubmed publisher
DeLucia D, Rinaldo C, Rappocciolo G. Inefficient HIV-1 trans Infection of CD4+ T Cells by Macrophages from HIV-1 Nonprogressors Is Associated with Altered Membrane Cholesterol and DC-SIGN. J Virol. 2018;92: pubmed publisher
Rodriguez Garcia M, Shen Z, Barr F, Boesch A, Ackerman M, Kappes J, et al. Dendritic cells from the human female reproductive tract rapidly capture and respond to HIV. Mucosal Immunol. 2017;10:531-544 pubmed publisher
Mesman A, de Vries R, McQuaid S, Duprex W, De Swart R, Geijtenbeek T. A prominent role for DC-SIGN+ dendritic cells in initiation and dissemination of measles virus infection in non-human primates. PLoS ONE. 2012;7:e49573 pubmed publisher
Novotny L, Clements J, Bakaletz L. Transcutaneous immunization as preventative and therapeutic regimens to protect against experimental otitis media due to nontypeable Haemophilus influenzae. Mucosal Immunol. 2011;4:456-67 pubmed publisher
product information
master code :
FAB161A
SKU :
FAB161A-100
product name :
Human DC-SIGN/CD209 APC-conjugated Antibody
unit size :
100 Tests (also 25 Tests)
description :
The Human DC-SIGN/CD209 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to DC-SIGN/CD209. This antibody reacts with chinchilla,human,macaca fascicularis fascicularis. The Human DC-SIGN/CD209 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
DC-SIGN/CD209
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
120507
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
NIH-3T3 mouse embryonic fibroblast cell line transfected with human DC-SIGN/CD209
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Chinchilla,Human
specificity :
Detects human DC-SIGN/CD209 on transfected NIH/3T3 cells and on monocyte derived dendritic cells. Does not react with parental mouse cells or irrelevant transfectants, such as human DC-SIGN2.
gene symbol :
CD209
top caption :
Detection of DC-SIGN/CD209 antibody in NIH-3T3 Mouse Cell Line Transfected with Human DC-SIGN/CD209 antibody by Flow Cytometry.
applications :
Flow Cytometry
extended description :
Clone 120507 was used by HLDA to establish CD designation
USD :
409 USD
product details :
Clone 120507 was used by HLDA to establish CD designation
alt names :
CD209, CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin, CD209 molecule, CDSIGNHIV gpl20-binding protein, CLEC4L, CLEC4LC-type lectin domain family 4 member L, DCSIGN, DC-SIGN1, DC-SIGN1C-type lectin domain family 4, member L, DC-SIGNMGC129965, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.