product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Rat CCR4 PE-conjugated Antibody
catalog :
FAB1567P-025
quantity :
25 Tests (also 100 Tests)
price :
159 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
205410
reactivity :
human, mouse, rat
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 21
Reference
Villegas J, Van Wassenhove J, Merrheim J, Matta K, Hamadache S, Flaug xe8 re C, et al. Blocking interleukin-23 ameliorates neuromuscular and thymic defects in myasthenia gravis. J Neuroinflammation. 2023;20:9 pubmed publisher
Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed publisher
Wang Z, Navarro Alvarez N, Shah J, Zhang H, Huang Q, Zheng Q, et al. Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Vet Immunol Immunopathol. 2016;182:150-158 pubmed publisher
Faulkner L, Gibson A, Sullivan A, Tailor A, Usui T, Alfirevic A, et al. Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity. Toxicol Sci. 2016;154:416-429 pubmed
Seumois G, Zapardiel Gonzalo J, White B, Singh D, Schulten V, Dillon M, et al. Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma. J Immunol. 2016;197:655-64 pubmed publisher
Wang Z, Pratts S, Zhang H, Spencer P, Yu R, Tonsho M, et al. Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Mol Oncol. 2016;10:553-65 pubmed publisher
Yang Y, Du L, Yang X, Qu A, Zhang X, Zhou C, et al. Aberrant CCR4 expression is involved in tumor invasion of lymph node-negative human gastric cancer. PLoS ONE. 2015;10:e0120059 pubmed publisher
Le Brocq M, Fraser A, Cotton G, Woznica K, McCulloch C, Hewitt K, et al. Chemokines as novel and versatile reagents for flow cytometry and cell sorting. J Immunol. 2014;192:6120-6130 pubmed publisher
Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, et al. Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer. J Transl Med. 2014;12:61 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Vasco C, Canazza A, Rizzo A, Mossa A, Corsini E, Silvani A, et al. Circulating T regulatory cells migration and phenotype in glioblastoma patients: an in vitro study. J Neurooncol. 2013;115:353-63 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, et al. CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses. J Immunol. 2010;184:1102-10 pubmed publisher
Barroso González J, El Jaber Vazdekis N, García Expósito L, Machado J, Zarate R, Ravelo A, et al. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities. J Biol Chem. 2009;284:16609-20 pubmed publisher
Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, et al. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J Allergy Clin Immunol. 2009;123:59-66.e4 pubmed publisher
Hartl D, Krauss Etschmann S, Koller B, Hordijk P, Kuijpers T, Hoffmann F, et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol. 2008;181:8053-67 pubmed
Muller A, Sonkoly E, Eulert C, Gerber P, Kubitza R, Schirlau K, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer. 2006;118:2147-57 pubmed
Piovan E, Tosello V, Indraccolo S, Cabrelle A, Baesso I, Trentin L, et al. Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation. Blood. 2005;105:931-9 pubmed
Corcione A, Casazza S, Ferretti E, Giunti D, Zappia E, Pistorio A, et al. Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis. Proc Natl Acad Sci U S A. 2004;101:11064-9 pubmed
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle M, et al. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J Leukoc Biol. 2003;73:584-90 pubmed
product information
master code :
FAB1567P
SKU :
FAB1567P-025
product name :
Human/Rat CCR4 PE-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Human/Rat CCR4 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCR4. This antibody reacts with human,mouse,porcine,rat. The Human/Rat CCR4 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
CCR4
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
205410
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Human CCR4 transfectants, Met1-Leu360, Accession # P51679
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Porcine,Rat
specificity :
Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects human CCR4 on human PBLs and platelets and rat CCR4 on rat splenocytes.
gene symbol :
CCR4
top caption :
Detection of CCR4 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
accessionNumbers :
P51679
applications :
Flow Cytometry
extended description :
Clone 205410 was used by HLDA to establish CD designation
USD :
159 USD
product details :
Clone 205410 was used by HLDA to establish CD designation
alt names :
C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4HGCN:14099, CCR-4, CD194, CD194 antigen, chemokine (C-C motif) receptor 4, chemokine (C-C) receptor 4, ChemR13, CKR4MGC88293, CMKBR4k5-5, K5-5
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.