This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human/Rat CCR4 Fluorescein-conjugated Antibody
catalog :
FAB1567F
quantity :
25 Tests (also 100 Tests)
price :
119 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
205410
reactivity :
human, rat
application :
flow cytometry
citations: 10
Reference
Kitadate A, Ikeda S, Abe F, Takahashi N, Shimizu N, Matsue K, et al. Histone deacetylase inhibitors downregulate CCR4 expression and decrease mogamulizumab efficacy in CCR4-positive mature T-cell lymphomas. Haematologica. 2018;103:126-135 pubmed publisher
Wang Z, Navarro Alvarez N, Shah J, Zhang H, Huang Q, Zheng Q, et al. Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Vet Immunol Immunopathol. 2016;182:150-158 pubmed publisher
Maghazachi A, Sand K, Al Jaderi Z. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity. Front Immunol. 2016;7:437 pubmed
James E, Gates T, LaFond R, Yamamoto S, Ni C, Mai D, et al. Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome. PLoS Pathog. 2016;12:e1005375 pubmed publisher
Pandya A, Al Jaderi Z, Høglund R, Holmøy T, Harbo H, Norgauer J, et al. Identification of human NK17/NK1 cells. PLoS ONE. 2011;6:e26780 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Brucklacher Waldert V, Steinbach K, Lioznov M, Kolster M, Holscher C, Tolosa E. Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression. J Immunol. 2009;183:5494-501 pubmed publisher
Finney O, Nwakanma D, Conway D, Walther M, Riley E. Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission. Eur J Immunol. 2009;39:1288-300 pubmed publisher
Baatar D, Olkhanud P, Newton D, Sumitomo K, Biragyn A. CCR4-expressing T cell tumors can be specifically controlled via delivery of toxins to chemokine receptors. J Immunol. 2007;179:1996-2004 pubmed
Garcia G, Humbert M, Capel F, Rimaniol A, Escourrou P, Emilie D, et al. Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis. Allergy. 2007;62:170-7 pubmed
product information
brand :
R&D Systems
master code :
FAB1567F
SKU :
FAB1567F-025
product name :
Human/Rat CCR4 Fluorescein-conjugated Antibody
description :
The Human/Rat CCR4 Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCR4. This antibody reacts with human, rat. The Human/Rat CCR4 Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
CCR4
category :
Primary Antibodies
unit size :
25 Tests (also 100 Tests)
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
205410
conjugate :
Fluorescein
host :
Mouse
immunogen :
Human CCR4 transfectants, Met1-Leu360, Accession # P51679
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human, Rat
specificity :
Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects human CCR4 on human PBLs and platelets and rat CCR4 on rat splenocytes.
gene symbol :
CCR4
catalog number base :
FAB1567F
accessionNumbers :
P51679
applications :
Flow Cytometry
extended description :
Clone 205410 was used by HLDA to establish CD designation
2020 USD :
119
2021 USD :
119 USD
product details :
Clone 205410 was used by HLDA to establish CD designation
alt names :
C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4HGCN:14099, CCR-4, CD194, CD194 antigen, chemokine (C-C motif) receptor 4, chemokine (C-C) receptor 4, ChemR13, CKR4MGC88293, CMKBR4k5-5, K5-5
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.