product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human PD-L1/B7-H1 PE-conjugated Antibody
catalog :
FAB1561P-100
quantity :
100 Tests
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
130021
reactivity :
human
application :
ELISA, flow cytometry
more info or order :
citations: 7
Reference
Wang B, Wang T, Yang C, Nan Z, Ai D, Wang X, et al. Co-inhibition of adenosine 2b receptor and programmed death-ligand 1 promotes the recruitment and cytotoxicity of natural killer cells in oral squamous cell carcinoma. Peerj. 2023;11:e15922 pubmed publisher
Tufano M, D Arrigo P, D Agostino M, Giordano C, Marrone L, Cesaro E, et al. PD-L1 Expression Fluctuates Concurrently with Cyclin D in Glioblastoma Cells. Cells. 2021;10: pubmed publisher
Mondelo Mac xed a P, Garc xed a Gonz xe1 lez J, Le xf3 n Mateos L, Anido U, Agu xed n S, Abdulkader I, et al. Clinical potential of circulating free DNA and circulating tumour cells in patients with metastatic non-small-cell lung cancer treated with pembrolizumab. Mol Oncol. 2021;15:2923-2940 pubmed publisher
Ouyang Y, Liu W, Zhang N, Yang X, Li J, Long S. Prognostic significance of programmed cell death-ligand 1 expression on circulating tumor cells in various cancers: A systematic review and meta-analysis. Cancer Med. 2021;10:7021-7039 pubmed publisher
Boyer M, Cayrefourcq L, Garima F, Foulongne V, Dereure O, Alix Panabières C. Circulating Tumor Cell Detection and Polyomavirus Status in Merkel Cell Carcinoma. Sci Rep. 2020;10:1612 pubmed publisher
Nicolazzo C, Raimondi C, Mancini M, Caponnetto S, Gradilone A, Gandini O, et al. Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab. Sci Rep. 2016;6:31726 pubmed publisher
Mazel M, Jacot W, Pantel K, Bartkowiak K, Topart D, Cayrefourcq L, et al. Frequent expression of PD-L1 on circulating breast cancer cells. Mol Oncol. 2015;9:1773-82 pubmed publisher
product information
master code :
FAB1561P
SKU :
FAB1561P-100
product name :
Human PD-L1/B7-H1 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human PD-L1/B7-H1 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to PD-L1. This antibody reacts with human. The Human PD-L1/B7-H1 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Cell Selection,ELISA Detection.
target :
PD-L1/B7-H1
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
130021
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human B7-H1/PD-L1, Phe19-Thr239, Accession # Q9NZQ7
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human B7-H1/PD-L1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) B7-1, -2, -H2, -H3, -H3b, -H4, rhPD-L2, recombinant mouse B7-H1, recombinant rat (rr) B7-1, or rrB7-2 is observed.
gene symbol :
CD274
top caption :
Detection of B7-H1/PD-L1 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
Q9NZQ7
applications :
Flow Cytometry,Cell Selection,ELISA Detection
USD :
439 USD
alt names :
Avelumab, B7-H, B7H1, B7-H1, B7H1PDCD1L1, CD274, CD274 antigenMGC142294, CD274 molecule, PDCD1L1, PDCD1LG1, PDCD1LG1MGC142296, PDL1, PD-L1, PD-L1B7 homolog 1, PDL1PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.