product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CCR3 PE-conjugated Antibody
catalog :
FAB155P-025
quantity :
25 Tests (also 100 Tests)
price :
149 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
61828
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Reference
Segal Salto M, Barashi N, Katav A, Edelshtein V, Aharon A, Hashmueli S, et al. A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage. JHEP Rep. 2020;2:100064 pubmed publisher
Catusse J, Leick M, Groch M, Clark D, Buchner M, Zirlik K, et al. Role of the atypical chemoattractant receptor CRAM in regulating CCL19 induced CCR7 responses in B-cell chronic lymphocytic leukemia. Mol Cancer. 2010;9:297 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Barroso González J, El Jaber Vazdekis N, García Expósito L, Machado J, Zarate R, Ravelo A, et al. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities. J Biol Chem. 2009;284:16609-20 pubmed publisher
Ahern D, Lloyd C, Robinson D. Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors. Allergy. 2009;64:1121-9 pubmed publisher
Hartl D, Krauss Etschmann S, Koller B, Hordijk P, Kuijpers T, Hoffmann F, et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol. 2008;181:8053-67 pubmed
Maru S, Holloway K, Flynn G, Lancashire C, Loughlin A, Male D, et al. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. J Neuroimmunol. 2008;199:35-45 pubmed publisher
Mårtensson U, Fenyo E, Olde B, Owman C. Characterization of the human chemerin receptor--ChemR23/CMKLR1--as co-receptor for human and simian immunodeficiency virus infection, and identification of virus-binding receptor domains. Virology. 2006;355:6-17 pubmed
Muller A, Sonkoly E, Eulert C, Gerber P, Kubitza R, Schirlau K, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer. 2006;118:2147-57 pubmed
Liu L, Jarjour N, Busse W, Kelly E. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge. J Allergy Clin Immunol. 2003;112:556-62 pubmed
Vanbervliet B, Homey B, Durand I, Massacrier C, Ait Yahia S, de Bouteiller O, et al. Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces. Eur J Immunol. 2002;32:231-42 pubmed
product information
master code :
FAB155P
SKU :
FAB155P-025
product name :
Human CCR3 PE-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Human CCR3 PE-conjugated Antibody from R&D Systems is a rat monoclonal antibody to CCR3. This antibody reacts with human. The Human CCR3 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
CCR3
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
61828
conjugate :
Phycoerythrin
host :
Rat
immunogen :
Y3 rat myeloid cell line transfected with human CCR3, Accession # P51677
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human CCR3 transfectants in flow cytometry. In flow cytometry, no cross-reactivity with CCR1, CCR2, CCR5, and CCR6 transfectants or the parental cell line is observed. Detects CCR3 on peripheral blood eosinophils.
gene symbol :
CCR3
top caption :
Detection of CCR3 antibody in Human Blood Granulocytes antibody by Flow Cytometry.
accessionNumbers :
P51677
applications :
Flow Cytometry
extended description :
Clone 61828 was used by HLDA to establish CD designation
USD :
149 USD
product details :
Clone 61828 was used by HLDA to establish CD designation
alt names :
b-chemokine receptor, CC chemokine receptor 3, C-C chemokine receptor type 3, C-C CKR-3, CCR3, CCR-3, CD193, CD193 antigen, chemokine (C-C motif) receptor 3, CKR3CC-CKR-3CMKBR3CD193, eosinophil CC chemokine receptor 3, Eosinophil eotaxin receptor, MGC102841
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.