product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Axl PE-conjugated Antibody
catalog :
FAB154P
quantity :
100 Tests
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
108724
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 11
Reference
Mytych J, Pan Z, Lopez Davis C, Redinger N, Lawrence C, Ziegler J, et al. Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3. bioRxiv. 2023;: pubmed publisher
Batur T, Argundogan A, Keles U, Mutlu Z, Alotaibi H, Senturk S, et al. AXL Knock-Out in SNU475 Hepatocellular Carcinoma Cells Provides Evidence for Lethal Effect Associated with G2 Arrest and Polyploidization. Int J Mol Sci. 2021;22: pubmed publisher
Liu Y, Wei J, Liu J, Ma W, Duan Y, Liu D. Novel AXL-targeted agents overcome FLT3 inhibitor resistance in FLT3-ITD+ acute myeloid leukemia cells. Oncol Lett. 2021;21:397 pubmed publisher
Boshuizen J, Vredevoogd D, Krijgsman O, Ligtenberg M, Blankenstein S, de Bruijn B, et al. Reversal of pre-existing NGFR-driven tumor and immune therapy resistance. Nat Commun. 2020;11:3946 pubmed publisher
Ruffin N, Gea Mallorquí E, Brouiller F, Jouve M, Silvin A, See P, et al. Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors. Proc Natl Acad Sci U S A. 2019;116:21685-21693 pubmed publisher
Axelrod H, Valkenburg K, Amend S, Hicks J, Parsana P, Torga G, et al. AXL Is a Putative Tumor Suppressor and Dormancy Regulator in Prostate Cancer. Mol Cancer Res. 2019;17:356-369 pubmed publisher
Chua B, Ngo J, Situ K, Ramirez C, Nakano H, Morizono K. Protein S and Gas6 induce efferocytosis of HIV-1-infected cells. Virology. 2018;515:176-190 pubmed publisher
Wang W, Zhao J, Wen X, Lin C, Li J, Huang Q, et al. MicroPET/CT Imaging of AXL Downregulation by HSP90 Inhibition in Triple-Negative Breast Cancer. Contrast Media Mol Imaging. 2017;2017:1686525 pubmed publisher
Yumoto K, Eber M, Wang J, Cackowski F, Decker A, Lee E, et al. Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow. Sci Rep. 2016;6:36520 pubmed publisher
Clark G, Kupresanin F, Fromm P, Ju X, Muusers L, Silveira P, et al. New insights into the phenotype of human dendritic cell populations. Clin Transl Immunology. 2016;5:e61 pubmed publisher
Zizzo G, Guerrieri J, Dittman L, Merrill J, Cohen P. Circulating levels of soluble MER in lupus reflect M2c activation of monocytes/macrophages, autoantibody specificities and disease activity. Arthritis Res Ther. 2013;15:R212 pubmed
product information
brand :
R&D Systems
master code :
FAB154P
SKU :
FAB154P
product name :
Human Axl PE-conjugated Antibody
unit size :
100 Tests
seo description :
The Human Axl PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Axl. This antibody reacts with human. The Human Axl PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,Knockout Validated.
target :
Axl
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
108724
conjugate :
Phycoerythrin
dilution :
Flow Cytometry 10 uL/10^6 cells, Knockout Validated 10 uL/10^6 cells
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Axl, Met1-Pro440, Accession # AAA61243
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Axl in direct ELISAs. In direct ELISAs, this antibody shows no cross-reactivity with recombinant mouse Axl, recombinant human (rh) Dtk or rhMer.
gene symbol :
AXL
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Axl antibody in HeLa Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
AAA61243
applications :
Knockout Validated,Flow Cytometry
USD :
449 USD
alt names :
AI323647, ARK, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming sequence/gene, EC 2.7.10, EC 2.7.10.1, JTK11, Tyro7, tyrosine-protein kinase receptor UFO, UFO, UFOoncogene AXL
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.