product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Axl Alexa Fluor« 488-conjugated Antibody
catalog :
FAB154G
quantity :
100 Tests
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
108724
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 10
Reference
Sulczewski F, Maqueda Alfaro R, Alc xe1 ntara Hern xe1 ndez M, Perez O, Saravanan S, Yun T, et al. Transitional dendritic cells are distinct from conventional DC2 precursors and mediate proinflammatory antiviral responses. Nat Immunol. 2023;24:1265-1280 pubmed publisher
Pop O, Geng A, Flint E, Singanayagam A, Ercan C, Possamai L, et al. AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells. Cell Mol Gastroenterol Hepatol. 2023;16:17-37 pubmed publisher
Bencze D, Fekete T, Pfliegler W, Sz xf6 x151 r x, Csoma E, Sz xe1 nt xf3 A, et al. Interactions between the NLRP3-Dependent IL-1β and the Type I Interferon Pathways in Human Plasmacytoid Dendritic Cells. Int J Mol Sci. 2022;23: pubmed publisher
Safaric Tepes P, Pal D, Lindsted T, Ibarra I, Lujambio A, Jimenez Sabinina V, et al. An epigenetic switch regulates the ontogeny of AXL-positive/EGFR-TKi-resistant cells by modulating miR-335 expression. elife. 2021;10: pubmed publisher
Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed publisher
Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
Balaji Ragunathrao V, Anwar M, Akhter M, Chavez A, Mao D, Natarajan V, et al. Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling. Cell Rep. 2019;29:3472-3487.e4 pubmed publisher
Brown C, Gudjonson H, Pritykin Y, Deep D, Lavallée V, Mendoza A, et al. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019;179:846-863.e24 pubmed publisher
Axelrod H, Valkenburg K, Amend S, Hicks J, Parsana P, Torga G, et al. AXL Is a Putative Tumor Suppressor and Dormancy Regulator in Prostate Cancer. Mol Cancer Res. 2019;17:356-369 pubmed publisher
Zheng S, Hedl M, Abraham C. TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. J Immunol. 2015;194:1928-37 pubmed publisher
product information
brand :
R&D Systems
master code :
FAB154G
SKU :
FAB154G
product name :
Human Axl Alexa Fluor« 488-conjugated Antibody
unit size :
100 Tests
seo description :
The Human Axl Alexa Fluor® 488-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Axl. This antibody reacts with human. The Human Axl Alexa Fluor® 488-conjugated Antibody has been validated for the following applications: Flow Cytometry,Knockout Validated.
target :
Axl
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
108724
conjugate :
Alexa Fluor 488
dilution :
Flow Cytometry 5 uL/10^6 cells, Knockout Validated 5 uL/10^6 cells
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Axl, Met1-Pro440, Accession # AAA61243
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Axl in direct ELISAs. In direct ELISAs, this antibody shows no cross-reactivity with recombinant mouse Axl, recombinant human (rh) Dtk or rhMer.
gene symbol :
AXL
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Axl antibody in HeLa Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
AAA61243
applications :
Knockout Validated,Flow Cytometry
USD :
449 USD
alt names :
AI323647, ARK, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming sequence/gene, EC 2.7.10, EC 2.7.10.1, JTK11, Tyro7, tyrosine-protein kinase receptor UFO, UFO, UFOoncogene AXL
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.