This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human CCR2 PE-conjugated Antibody
catalog :
FAB151P
quantity :
25 Tests (also 100 Tests)
price :
139 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
48607
reactivity :
human
application :
flow cytometry
citations: 33
Reference
Cantero Pérez J, Grau Expósito J, Serra Peinado C, Rosero D, Luque Ballesteros L, Astorga Gamaza A, et al. Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa. Nat Commun. 2019;10:4739 pubmed publisher
Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
Walscheid K, Weinhage T, Foell D, Heinz C, Kasper M, Heiligenhaus A. Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis. Clin Immunol. 2016;: pubmed publisher
Monsuur H, Weijers E, Niessen F, Gefen A, Koolwijk P, Gibbs S, et al. Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering. PLoS ONE. 2016;11:e0167056 pubmed publisher
Faivre V, Lukaszewicz A, Payen D. Downregulation of Blood Monocyte HLA-DR in ICU Patients Is Also Present in Bone Marrow Cells. PLoS ONE. 2016;11:e0164489 pubmed publisher
Lau G, Labrecque J, Metz M, Vaz R, Fricker S. Specificity for a CCR5 Inhibitor Is Conferred by a Single Amino Acid Residue: ROLE OF ILE198. J Biol Chem. 2015;290:11041-51 pubmed publisher
Carvallo L, Lopez L, Che F, Lim J, Eugenin E, Williams D, et al. Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes. J Immunol. 2015;194:3246-58 pubmed publisher
Falk M, Singh A, Faber C, Nissen M, Hviid T, Sørensen T. CX3CL1/CX3CR1 and CCL2/CCR2 chemokine/chemokine receptor complex in patients with AMD. PLoS ONE. 2014;9:e112473 pubmed publisher
Bednar F, Song C, Bardi G, Cornwell W, Rogers T. Cross-desensitization of CCR1, but not CCR2, following activation of the formyl peptide receptor FPR1. J Immunol. 2014;192:5305-13 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Vujanovic L, Ballard W, Thorne S, Vujanovic N, Butterfield L. Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10. Oncoimmunology. 2012;1:448-457 pubmed
Badr G, Lefevre E, Mohany M. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE. 2011;6:e23741 pubmed publisher
Craddock J, Lu A, Bear A, Pule M, Brenner M, Rooney C, et al. Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother. 2010;33:780-8 pubmed publisher
Röhrl J, Yang D, Oppenheim J, Hehlgans T. Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. J Immunol. 2010;184:6688-94 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, et al. CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses. J Immunol. 2010;184:1102-10 pubmed publisher
Tsujioka H, Imanishi T, Ikejima H, Kuroi A, Takarada S, Tanimoto T, et al. Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. J Am Coll Cardiol. 2009;54:130-8 pubmed publisher
Barroso González J, El Jaber Vazdekis N, García Expósito L, Machado J, Zarate R, Ravelo A, et al. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities. J Biol Chem. 2009;284:16609-20 pubmed publisher
Hartl D, Krauss Etschmann S, Koller B, Hordijk P, Kuijpers T, Hoffmann F, et al. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol. 2008;181:8053-67 pubmed
Ling B, Veazey R, Marx P. Nonpathogenic CCR2-tropic SIVrcm after serial passage and its effect on SIVmac infection of Indian rhesus macaques. Virology. 2008;379:38-44 pubmed publisher
Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes. J Leukoc Biol. 2008;84:1109-19 pubmed publisher
Maru S, Holloway K, Flynn G, Lancashire C, Loughlin A, Male D, et al. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. J Neuroimmunol. 2008;199:35-45 pubmed publisher
Pokkali S, Das S, R L. Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. Cytokine. 2008;41:307-14 pubmed publisher
Freeman C, Curtis J, Chensue S. CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity. Am J Pathol. 2007;171:767-76 pubmed
Dhillon N, Pinson D, Dhillon S, Tawfik O, Danley M, Davis M, et al. Bleomycin treatment causes enhancement of virus replication in the lungs of SHIV-infected macaques. Am J Physiol Lung Cell Mol Physiol. 2007;292:L1233-40 pubmed
Bestebroer J, Poppelier M, Ulfman L, Lenting P, Denis C, Van Kessel K, et al. Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling. Blood. 2007;109:2936-43 pubmed
Muller A, Sonkoly E, Eulert C, Gerber P, Kubitza R, Schirlau K, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer. 2006;118:2147-57 pubmed
Gessler P, Pretre R, Hohl V, Rousson V, Fischer J, Dahinden C. CXC-chemokine stimulation of neutrophils correlates with plasma levels of myeloperoxidase and lactoferrin and contributes to clinical outcome after pediatric cardiac surgery. Shock. 2004;22:513-20 pubmed
Piovan E, Tosello V, Indraccolo S, Cabrelle A, Baesso I, Trentin L, et al. Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation. Blood. 2005;105:931-9 pubmed
Corcione A, Casazza S, Ferretti E, Giunti D, Zappia E, Pistorio A, et al. Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis. Proc Natl Acad Sci U S A. 2004;101:11064-9 pubmed
Liu L, Jarjour N, Busse W, Kelly E. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge. J Allergy Clin Immunol. 2003;112:556-62 pubmed
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle M, et al. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J Leukoc Biol. 2003;73:584-90 pubmed
Vanbervliet B, Homey B, Durand I, Massacrier C, Ait Yahia S, de Bouteiller O, et al. Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces. Eur J Immunol. 2002;32:231-42 pubmed
product information
brand :
R&D Systems
master code :
FAB151P
SKU :
FAB151P-025
product name :
Human CCR2 PE-conjugated Antibody
description :
The Human CCR2 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCR2. This antibody reacts with human. The Human CCR2 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
CCR2
category :
Primary Antibodies
unit size :
25 Tests (also 100 Tests)
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
48607
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
NS0 mouse myeloma cell line transfected with human CCR2, Met1-Leu360, Accession # NP_001116868
isotype :
IgG2b
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human CCR-2 transfectants but not the parental cell line or CCR-5 transfectants.
gene symbol :
CCR2
catalog number base :
FAB151P
accessionNumbers :
NP_001116868
applications :
Flow Cytometry
extended description :
Clone 48607 was used by HLDA to establish CD designation
2020 USD :
139
2021 USD :
139 USD
product details :
Clone 48607 was used by HLDA to establish CD designation
alt names :
C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.