Human CCR2 PE-conjugated Antibody | R&D Systems FAB151P-025 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR2 PE-conjugated Antibody

catalog :

FAB151P-025

quantity :

25 Tests (also 100 Tests)

price :

179 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

48607

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 44

Reference
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Masselli E, Carubbi C, Pozzi G, Percesepe A, Campanelli R, Villani L, et al. Impact of the rs1024611 Polymorphism of CCL2 on the Pathophysiology and Outcome of Primary Myelofibrosis. Cancers (Basel). 2021;13: pubmed publisher
Krychtiuk K, Lenz M, Richter B, Hohensinner P, Kastl S, Mangold A, et al. Monocyte subsets predict mortality after cardiac arrest. J Leukoc Biol. 2021;109:1139-1146 pubmed publisher
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Yao M, Fang W, Smart C, Hu Q, Huang S, Alvarez N, et al. CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation. Mol Cancer Res. 2019;17:604-617 pubmed publisher
Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
Walscheid K, Weinhage T, Foell D, Heinz C, Kasper M, Heiligenhaus A. Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis. Clin Immunol. 2016;: pubmed publisher
Monsuur H, Weijers E, Niessen F, Gefen A, Koolwijk P, Gibbs S, et al. Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering. PLoS ONE. 2016;11:e0167056 pubmed publisher
Faivre V, Lukaszewicz A, Payen D. Downregulation of Blood Monocyte HLA-DR in ICU Patients Is Also Present in Bone Marrow Cells. PLoS ONE. 2016;11:e0164489 pubmed publisher
Lau G, Labrecque J, Metz M, Vaz R, Fricker S. Specificity for a CCR5 Inhibitor Is Conferred by a Single Amino Acid Residue: ROLE OF ILE198. J Biol Chem. 2015;290:11041-51 pubmed publisher
Carvallo L, Lopez L, Che F, Lim J, Eugenin E, Williams D, et al. Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes. J Immunol. 2015;194:3246-58 pubmed publisher
Falk M, Singh A, Faber C, Nissen M, Hviid T, SÃ¸rensen T. CX3CL1/CX3CR1 and CCL2/CCR2 chemokine/chemokine receptor complex in patients with AMD. PLoS ONE. 2014;9:e112473 pubmed publisher
Bednar F, Song C, Bardi G, Cornwell W, Rogers T. Cross-desensitization of CCR1, but not CCR2, following activation of the formyl peptide receptor FPR1. J Immunol. 2014;192:5305-13 pubmed publisher
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher
Vasco C, Canazza A, Rizzo A, Mossa A, Corsini E, Silvani A, et al. Circulating T regulatory cells migration and phenotype in glioblastoma patients: an in vitro study. J Neurooncol. 2013;115:353-63 pubmed publisher
Liu K, Dorovini Zis K. Differential regulation of CD4+ T cell adhesion to cerebral microvascular endothelium by the β-chemokines CCL2 and CCL3. Int J Mol Sci. 2012;13:16119-40 pubmed publisher
Al ofi E, Coffelt S, Anumba D. Monocyte subpopulations from pre-eclamptic patients are abnormally skewed and exhibit exaggerated responses to Toll-like receptor ligands. PLoS ONE. 2012;7:e42217 pubmed publisher
Vujanovic L, Ballard W, Thorne S, Vujanovic N, Butterfield L. Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10. Oncoimmunology. 2012;1:448-457 pubmed
Badr G, Lefevre E, Mohany M. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE. 2011;6:e23741 pubmed publisher
Craddock J, Lu A, Bear A, Pule M, Brenner M, Rooney C, et al. Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother. 2010;33:780-8 pubmed publisher
Röhrl J, Yang D, Oppenheim J, Hehlgans T. Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. J Immunol. 2010;184:6688-94 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
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product information

brand :

R&D Systems

master code :

FAB151P

SKU :

FAB151P-025

product name :

Human CCR2 PE-conjugated Antibody

unit size :

25 Tests (also 100 Tests)

seo description :

The Human CCR2 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to CCR2. This antibody reacts with human,primate - macaca mulatta (rhesus macaque). The Human CCR2 PE-conjugated Antibody has been validated for the following applications: CAR-T (Flow Cytometry),Flow Cytometry.

target :

CCR2

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

48607

conjugate :

Phycoerythrin

dilution :

Flow Cytometry 10 uL/10^6 cells

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CCR2, Met1-Leu360, Accession # NP_001116868

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human CCR-2 transfectants but not the parental cell line or CCR-5 transfectants.

gene symbol :

CCR2

top caption :

Detection of CCR2 antibody in Human PBMCs antibody by Flow Cytometry.

accessionNumbers :

NP_001116868

applications :

CAR-T (Flow Cytometry),Flow Cytometry

extended description :

Clone 48607 was used by HLDA to establish CD designation

USD :

179 USD

product details :

Clone 48607 was used by HLDA to establish CD designation

alt names :

C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage