Human CCR2 Biotinylated Antibody | R&D Systems FAB151B product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR2 Biotinylated Antibody

catalog :

FAB151B

quantity :

100 Tests

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

48607

reactivity :

human

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Parween F, Singh S, Kathuria N, Zhang H, Ashida S, Otaizo Carrasquero F, et al. Migration arrest and transendothelial trafficking of human pathogenic-like Th17 cells are mediated by differentially positioned chemokines. Nat Commun. 2025;16:1978 pubmed publisher
Parween F, Singh S, Zhang H, Kathuria N, Otaizo Carrasquero F, Shamsaddini A, et al. Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells. bioRxiv. 2023;: pubmed publisher
Lee C, Zhang H, Singh S, Koo L, Kabat J, Tsang H, et al. C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation. elife. 2018;7: pubmed publisher
Sato W, Tomita A, Ichikawa D, Lin Y, Kishida H, Miyake S, et al. CCR2(+)CCR5(+) T cells produce matrix metalloproteinase-9 and osteopontin in the pathogenesis of multiple sclerosis. J Immunol. 2012;189:5057-65 pubmed publisher
Zhang H, Song K, Rabin R, Hill B, Perfetto S, Roederer M, et al. CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response. J Immunol. 2010;185:6646-63 pubmed publisher
Dagouassat M, Suffee N, Hlawaty H, Haddad O, Charni F, Laguillier C, et al. Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. Int J Cancer. 2010;126:1095-108 pubmed publisher
Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol. 2007;179:4272-82 pubmed
Sato W, Aranami T, Yamamura T. Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype. J Immunol. 2007;178:7525-9 pubmed

product information

brand :

R&D Systems

catalog number base :

FAB151B

SKU :

FAB151B

product name :

Human CCR2 Biotinylated Antibody

units size :

100 Tests

description :

The Human CCR2 Biotinylated Antibody from R&D Systems is a mouse monoclonal antibody to CCR2. This antibody reacts with human. The Human CCR2 Biotinylated Antibody has been validated for the following applications: Neutralizing,Flow Cytometry.

target :

CCR2

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

48607

conjugate :

Biotin

all_available conjugate :

Biotin

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CCR2, Met1-Leu360, Accession # NP_001116868

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CCR2 transfectants but not the parental cell line or CCR5 transfectants.

gene symbol :

CCR2

top caption :

Detection of CCR2 antibody in Human PBMCs antibody by Flow Cytometry.

accessionNumbers :

NP_001116868

applications :

Neutralizing,Flow Cytometry

extended description :

Clone 48607 was used by HLDA to establish CD designation

USD :

359 USD

product details :

Clone 48607 was used by HLDA to establish CD designation

alt names :

C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor

storage :

Do not freeze. 12 months from date of receipt, 2 to 8 Â°C as supplied.

more info or order :

R&D Systems product webpage