Human CCR2 Biotinylated Antibody | R&D Systems FAB151B product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCR2 Biotinylated Antibody

catalog :

FAB151B

quantity :

100 Tests

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

48607

reactivity :

human

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 7

Reference
Parween F, Singh S, Zhang H, Kathuria N, Otaizo Carrasquero F, Shamsaddini A, et al. Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells. bioRxiv. 2023;: pubmed publisher
Lee C, Zhang H, Singh S, Koo L, Kabat J, Tsang H, et al. C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation. elife. 2018;7: pubmed publisher
Sato W, Tomita A, Ichikawa D, Lin Y, Kishida H, Miyake S, et al. CCR2(+)CCR5(+) T cells produce matrix metalloproteinase-9 and osteopontin in the pathogenesis of multiple sclerosis. J Immunol. 2012;189:5057-65 pubmed publisher
Zhang H, Song K, Rabin R, Hill B, Perfetto S, Roederer M, et al. CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response. J Immunol. 2010;185:6646-63 pubmed publisher
Dagouassat M, Suffee N, Hlawaty H, Haddad O, Charni F, Laguillier C, et al. Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. Int J Cancer. 2010;126:1095-108 pubmed publisher
Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol. 2007;179:4272-82 pubmed
Sato W, Aranami T, Yamamura T. Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype. J Immunol. 2007;178:7525-9 pubmed

product information

master code :

FAB151B

SKU :

FAB151B

product name :

Human CCR2 Biotinylated Antibody

unit size :

100 Tests

description :

The Human CCR2 Biotinylated Antibody from R&D Systems is a mouse monoclonal antibody to CCR2. This antibody reacts with human. The Human CCR2 Biotinylated Antibody has been validated for the following applications: Neutralizing,Flow Cytometry.

target :

CCR2

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

48607

conjugate :

Biotin

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CCR2, Met1-Leu360, Accession # NP_001116868

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CCR2 transfectants but not the parental cell line or CCR5 transfectants.

gene symbol :

CCR2

top caption :

Detection of CCR2 antibody in Human PBMCs antibody by Flow Cytometry.

accessionNumbers :

NP_001116868

applications :

Neutralizing,Flow Cytometry

extended description :

Clone 48607 was used by HLDA to establish CD designation

USD :

359 USD

product details :

Clone 48607 was used by HLDA to establish CD designation

alt names :

C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor

storage :

Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage