Human Glut1 Fluorescein-conjugated Antibody | R&D Systems FAB1418F product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Glut1 Fluorescein-conjugated Antibody

catalog :

FAB1418F

quantity :

100 Tests

price :

349 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

202915

reactivity :

human

application :

flow cytometry

more info or order :

R&D Systems product webpage

citations: 11

Reference
Selvakumaran J, Ursu S, Bowerman M, Lu Nguyen N, Wood M, Malerba A, et al. An Induced Pluripotent Stem Cell-Derived Human Blood-Brain Barrier (BBB) Model to Test the Crossing by Adeno-Associated Virus (AAV) Vectors and Antisense Oligonucleotides. Biomedicines. 2023;11: pubmed publisher
Akusjärvi S, Ambikan A, Krishnan S, Gupta S, Sperk M, Vegvari A, et al. Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling. iScience. 2022;25:103607 pubmed publisher
Portillo A, Hogg R, Poznanski S, Rojas E, Cashell N, Hammill J, et al. Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors. iScience. 2021;24:102619 pubmed publisher
Lin H, Chen Y, Wei Y, Chuang Y, Hsieh S, Hsieh J, et al. Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition. Int J Mol Sci. 2020;21: pubmed publisher
Barili V, Fisicaro P, Montanini B, Acerbi G, Filippi A, Forleo G, et al. Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection. Nat Commun. 2020;11:604 pubmed publisher
Ricciardi S, Manfrini N, Alfieri R, Calamita P, Crosti M, Gallo S, et al. The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling. Cell Metab. 2018;28:895-906.e5 pubmed publisher
Yeoh H, Cheng A, Cherry C, Weir J, Meikle P, Hoy J, et al. Immunometabolic and Lipidomic Markers Associated With the Frailty Index and Quality of Life in Aging HIV+ Men on Antiretroviral Therapy. EBioMedicine. 2017;22:112-121 pubmed publisher
Patsoukis N, Bardhan K, Chatterjee P, Sari D, Liu B, Bell L, et al. PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. Nat Commun. 2015;6:6692 pubmed publisher
Maeda Y, Terasawa H, Tanaka Y, Mitsuura C, Nakashima K, Yusa K, et al. Separate cellular localizations of human T-lymphotropic virus 1 (HTLV-1) Env and glucose transporter type 1 (GLUT1) are required for HTLV-1 Env-mediated fusion and infection. J Virol. 2015;89:502-11 pubmed publisher
Huang L, Nakayama H, Klagsbrun M, Mulliken J, Bischoff J. Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells. Stem Cells. 2015;33:133-45 pubmed publisher
Palmer C, Ostrowski M, Gouillou M, Tsai L, Yu D, Zhou J, et al. Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection. AIDS. 2014;28:297-309 pubmed publisher

product information

master code :

FAB1418F

SKU :

FAB1418F

product name :

Human Glut1 Fluorescein-conjugated Antibody

unit size :

100 Tests

description :

The Human Glut1 Fluorescein-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to Glut1. This antibody reacts with human. The Human Glut1 Fluorescein-conjugated Antibody has been validated for the following applications: Flow Cytometry.

target :

Glut1

category :

Primary Antibodies

buffer :

Supplied in a saline solution containing BSA and Sodium Azide.

clonality :

Monoclonal

clone :

202915

conjugate :

Fluorescein

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human Glut1, Met1-Val492, Accession # AAA52571

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Glut1. Stains human Glut1-transfected NS0 cells, but not NS0 control transfectants. Although Human Glut1 Antibody detects Glut1 on the surface of T cells (1, 2), it does not detect it on erythrocytes (5). The reason for this discrepancy is not understood, but may be related to conformational or post-translational modification differences.

gene symbol :

SLC2A1

top caption :

Detection of Glut1 antibody in HepG2 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

AAA52571

applications :

Flow Cytometry

USD :

349 USD

alt names :

Choreoathetosis/Spasticity, Episodic (Paroxysmal Choreoathetosis), CSE, DYT17, DYT18, DYT9, EIG12, Glucose transporter type 1, erythrocyte/brain, GLUT-1, GLUT1DS, HepG2 glucose transporter, HTLVR, Human T-Cell Leukemia Virus (I and II) Receptor, MGC141895, MGC141896, PED, SLC2A1, solute carrier family 2 (facilitated glucose transporter), member 1, Solute Carrier Family 2 Member 1, solute carrier family 2, facilitated glucose transporter member 1

storage :

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.

more info or order :

R&D Systems product webpage