This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
NKG2D / CD314 Alexa Fluor 750-conjugated Antibody
catalog :
FAB139S
quantity :
100 ug
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
149810
reactivity :
human
application :
flow cytometry, blocking or activating experiments
citations: 11
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; loading ...; fig 5a
Dassa L, Seidel E, Oiknine Djian E, Yamin R, Wolf D, Le Trilling V, et al. The Human Cytomegalovirus Protein UL148A Downregulates the NK Cell-Activating Ligand MICA To Avoid NK Cell Attack. J Virol. 2018;92: pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 5
Djaoud Z, Guethlein L, Horowitz A, Azzi T, Nemat Gorgani N, Olive D, et al. Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and ?? T cells. J Exp Med. 2017;214:1827-1841 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig s14b
  • flow cytometry; human
Kwon H, Choi G, Ryu S, Kwon S, Kim S, Booth C, et al. Stepwise phosphorylation of p65 promotes NF-?B activation and NK cell responses during target cell recognition. Nat Commun. 2016;7:11686 pubmed publisher
Muller Durovic B, Grählert J, Devine O, Akbar A, Hess C. CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. Aging (Albany NY). 2019;11:724-740 pubmed publisher
Nam H, Cho Y, Lim J, Kim S, Kim H, Sim S, et al. Functional status of immune cells in patients with long-lasting type 2 diabetes mellitus. Clin Exp Immunol. 2018;194:125-136 pubmed publisher
Dai Y, Liu H, Liu Y, Zhang Y, He W. EBV transformation induces overexpression of hMSH2/3/6 on B lymphocytes and enhances γδT-cell-mediated cytotoxicity via TCR and NKG2D. Immunology. 2018;: pubmed publisher
Sharma N, Trinidad C, Trembath A, Markiewicz M. NKG2D Signaling between Human NK Cells Enhances TACE-Mediated TNF-α Release. J Immunol. 2017;199:2865-2872 pubmed publisher
Jensen H, Chen S, Folkersen L, Nolan G, Lanier L. EBI3 regulates the NK cell response to mouse cytomegalovirus infection. Proc Natl Acad Sci U S A. 2017;114:1625-1630 pubmed publisher
Guenot M, Loizon S, Howard J, Costa G, Baker D, Mohabeer S, et al. Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells. Infect Immun. 2015;83:3816-24 pubmed publisher
Ghiringhelli F, Menard C, Terme M, Flament C, Taieb J, Chaput N, et al. CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner. J Exp Med. 2005;202:1075-85 pubmed
Halary F, Pitard V, Dlubek D, Krzysiek R, de la Salle H, Merville P, et al. Shared reactivity of V{delta}2(neg) {gamma}{delta} T cells against cytomegalovirus-infected cells and tumor intestinal epithelial cells. J Exp Med. 2005;201:1567-78 pubmed
product information
SKU :
FAB139S-100UG
product name :
NKG2D / CD314 Alexa Fluor 750-conjugated Antibody
unit size :
100 ug
Description :
The Human NKG2D/CD314 Alexa Fluor® 750-conjugated Antibody from R D Systems is a mouse monoclonal antibody to NKG2D/CD314. This antibody reacts with human. The Human NKG2D/CD314 Alexa Fluor® 750-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
NKG2D / CD314
category :
Primary Antibodies
buffer :
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
149810
concentration :
0.2 mg/ml
conjugate :
Alexa Fluor 750
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human NKG2D / CD314
isotype :
IgG1
species :
Human
specificity :
Detects human NKG2D / CD314 in Western blots.
gene symbol :
KLRK1
catalog number base :
FAB139S
applications :
Flow Cytometry
extended description :
Clone 149810 was used by HLDA to establish CD designation
2020 Proposedprice USD :
299 USD
product details :
Clone 149810 was used by HLDA to establish CD designation
alt names :
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, KLRK1, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
storage :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.