product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NKG2D/CD314 APC-conjugated Antibody
catalog :
FAB139A-025
quantity :
25 Tests (also 100 Tests)
price :
139 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
149810
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Reference
Sornkayasit K, Jumnainsong A, Phoksawat W, Eungpinichpong W, Leelayuwat C. Traditional Thai Massage Promoted Immunity in the Elderly via Attenuation of Senescent CD4+ T Cell Subsets: A Randomized Crossover Study. Int J Environ Res Public Health. 2021;18: pubmed publisher
Møller S, Mellergaard M, Madsen M, Bermejo A, Jepsen S, Hansen M, et al. Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells. Front Immunol. 2020;11:1968 pubmed publisher
Høgh R, Droujinine A, Møller S, Jepsen S, Mellergaard M, Andresen L, et al. Fumarate Upregulates Surface Expression of ULBP2/ULBP5 by Scavenging Glutathione Antioxidant Capacity. J Immunol. 2020;204:1746-1759 pubmed publisher
Schilbach K, Welker C, Krickeberg N, Kai xdf er C, Schleicher S, Hashimoto H. In the Absence of a TCR Signal IL-2/IL-12/18-Stimulated γδ T Cells Demonstrate Potent Anti-Tumoral Function Through Direct Killing and Senescence Induction in Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher
Song H, Kim Y, Park G, Kim Y, Kim S, Lee H, et al. Transforming growth factor-β1 regulates human renal proximal tubular epithelial cell susceptibility to natural killer cells via modulation of the NKG2D ligands. Int J Mol Med. 2015;36:1180-8 pubmed publisher
Uhlenbrock F, Hagemann Jensen M, Kehlet S, Andresen L, Pastorekova S, Skov S. The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway. J Immunol. 2014;193:1654-65 pubmed publisher
Reichwald K, Jørgensen T, Tougaard P, Skov S. TL1A induces TCR independent IL-6 and TNF-? production and growth of PLZF? leukocytes. PLoS ONE. 2014;9:e85793 pubmed publisher
Markel G, Seidman R, Besser M, Zabari N, Ortenberg R, Shapira R, et al. Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells. PLoS ONE. 2009;4:e5597 pubmed publisher
Vossen M, Matmati M, Hertoghs K, Baars P, Gent M, Leclercq G, et al. CD27 defines phenotypically and functionally different human NK cell subsets. J Immunol. 2008;180:3739-45 pubmed
Kim Y, Han M, Broxmeyer H. 4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells. Blood. 2008;111:1378-86 pubmed
Viey E, Fromont G, Escudier B, Morel Y, Da Rocha S, Chouaib S, et al. Phosphostim-activated gamma delta T cells kill autologous metastatic renal cell carcinoma. J Immunol. 2005;174:1338-47 pubmed
product information
brand :
R&D Systems
master code :
FAB139A
SKU :
FAB139A-025
product name :
Human NKG2D/CD314 APC-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
seo description :
The Human NKG2D/CD314 APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to NKG2D/CD314. This antibody reacts with human. The Human NKG2D/CD314 APC-conjugated Antibody has been validated for the following applications: Flow Cytometry,Functional Assay.
target :
NKG2D/CD314
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
149810
conjugate :
Allophycocyanin
dilution :
Flow Cytometry 10 uL/10^6 cells
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human NKG2D/CD314
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human NKG2D/CD314 in Western blots.
gene symbol :
KLRK1
top caption :
Detection of NKG2D/CD314 antibody in Human PBMCs antibody by Flow Cytometry.
applications :
Flow Cytometry,Functional Assay
extended description :
Clone 149810 was used by HLDA to establish CD designation
USD :
139 USD
product details :
Clone 149810 was used by HLDA to establish CD designation
alt names :
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, KLRK1, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.