product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NKG2C/CD159c Alexa Fluor« 488-conjugated Antibody
catalog :
FAB138G-025
quantity :
25 Tests (also 100 Tests)
price :
179 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
134591
reactivity :
human
application :
flow cytometry
more info or order :
citations: 14
Reference
Ulvmoen A, Greiff V, Bechensteen A, Inngjerdingen M. NKG2A discriminates natural killer cells with a suppressed phenotype in pediatric acute leukemia. J Leukoc Biol. 2024;115:334-343 pubmed publisher
Huuhtanen J, Kasanen H, Peltola K, L xf6 nnberg T, Glumoff V, Br xfc ck O, et al. Single-cell characterization of anti-LAG-3 and anti-PD-1 combination treatment in patients with melanoma. J Clin Invest. 2023;133: pubmed publisher
Fernandez R, Mayoral J, Pierre Louis L, Yao Y, Xu Y, Mu S, et al. Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15. Blood Adv. 2023;7:9-19 pubmed publisher
Palamarchuk A, Alekseeva N, Streltsova M, Ustiuzhanina M, Kobyzeva P, Kust S, et al. Increased Susceptibility of the CD57- NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response. Int J Mol Sci. 2021;22: pubmed publisher
Nagano S, Maeda T, Ichise H, Kashima S, Ohtaka M, Nakanishi M, et al. High Frequency Production of T Cell-Derived iPSC Clones Capable of Generating Potent Cytotoxic T Cells. Mol Ther Methods Clin Dev. 2020;16:126-135 pubmed publisher
Calabrese D, Chong T, Wang A, Singer J, Gottschall M, Hays S, et al. NKG2C Natural Killer Cells in Bronchoalveolar Lavage Are Associated With Cytomegalovirus Viremia and Poor Outcomes in Lung Allograft Recipients. Transplantation. 2019;103:493-501 pubmed publisher
Nuñez S, Ziblat A, Secchiari F, Torres N, Sierra J, Raffo Iraolagoitia X, et al. Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-? and Engagement of CD85j. J Immunol. 2018;200:1008-1015 pubmed publisher
Rechtien A, Richert L, Lorenzo H, Martrus G, Hejblum B, Dahlke C, et al. Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV. Cell Rep. 2017;20:2251-2261 pubmed publisher
Kovalenko E, Streltsova M, Kanevskiy L, Erokhina S, Telford W. Identification of Human Memory-Like NK Cells. Curr Protoc Cytom. 2017;79:9.50.1-9.50.11 pubmed publisher
Sim M, Stowell J, Sergeant R, Altmann D, Long E, Boyton R. KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells. Eur J Immunol. 2016;46:185-91 pubmed publisher
Spallanzani R, Torres N, Avila D, Ziblat A, Iraolagoitia X, Rossi L, et al. Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors. J Immunol. 2015;195:2141-8 pubmed publisher
Dunphy S, Guinan K, Chorcora C, Jayaraman J, Traherne J, Trowsdale J, et al. 2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells. Genes Immun. 2015;16:301-10 pubmed publisher
Katano I, Takahashi T, Ito R, Kamisako T, Mizusawa T, Ka Y, et al. Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse. J Immunol. 2015;194:3513-25 pubmed publisher
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol. 2013;43:480-7 pubmed publisher
product information
brand :
R&D Systems
master code :
FAB138G
SKU :
FAB138G-025
product name :
Human NKG2C/CD159c Alexa Fluor« 488-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
seo description :
The Human NKG2C/CD159c Alexa Fluor® 488-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to NKG2C/CD159c/KLRC2. This antibody reacts with human. The Human NKG2C/CD159c Alexa Fluor® 488-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
NKG2C/CD159c
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
134591
conjugate :
Alexa Fluor 488
dilution :
Flow Cytometry 5 uL/10^6 cells
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.
gene symbol :
KLRC2
top caption :
Detection of NKG2C/CD159c antibody in Human PBMC lymphocytes antibody by Flow Cytometry.
applications :
Flow Cytometry
USD :
179 USD
alt names :
CD159 antigen-like family member C, CD159c, CD159c antigen, killer cell lectin-like receptor subfamily C, member 2, KLRC2, MGC138244, NK cell receptor C, NKG2-C, NKG2-C type II integral membrane protein, NKG2CNKG2-C-activating NK receptor
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.