product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NKG2C/CD159c APC-conjugated Antibody
catalog :
FAB138A-025
quantity :
25 Tests (also 100 Tests)
price :
189 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
134591
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 20
Reference
Santos A, van Unen V, Lin Z, Chirieleison S, Ha N, Batish A, et al. A human autoimmune organoid model reveals IL-7 function in coeliac disease. Nature. 2024;632:401-410 pubmed publisher
Palamarchuk A, Kovalenko E, Streltsova M. The hTERT and iCasp9 Transgenes Affect EOMES and T-BET Levels in NK Cells and the Introduction of Both Genes Improves NK Cell Proliferation in Response to IL2 and IL15 Stimulation. Biomedicines. 2024;12: pubmed publisher
Boudreau C, Burke J, Yousif A, Sangesland M, Jastrzebski S, Verschoor C, et al. Antibody-mediated NK cell activation as a correlate of immunity against influenza infection. Nat Commun. 2023;14:5170 pubmed publisher
Choi S, Koh J, Rha M, Seo I, Lee H, Jeong S, et al. KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans. Cell Rep. 2023;42:112236 pubmed publisher
Chimienti R, Baccega T, Torchio S, Manenti F, Pellegrini S, Cospito A, et al. Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for β cell replacement. Cell Rep. 2022;40:111423 pubmed publisher
Shemesh A, Su Y, Calabrese D, Chen D, Arakawa Hoyt J, Roybal K, et al. Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression. J Exp Med. 2022;219: pubmed publisher
Teramo A, Binatti A, Ciabatti E, Schiavoni G, Tarrini G, Baril xe0 G, et al. Defining TCRγδ lymphoproliferative disorders by combined immunophenotypic and molecular evaluation. Nat Commun. 2022;13:3298 pubmed publisher
Ariyanto I, Estiasari R, Karim B, Wijaya I, Bela B, Soebandrio A, et al. Which NK cell populations mark the high burden of CMV present in all HIV patients beginning ART in Indonesia?. AIDS Res Ther. 2022;19:16 pubmed publisher
Waters S, Lee S, Irish A, Price P. Challenging the Conventional Interpretation of HCMV Seronegativity. Microorganisms. 2021;9: pubmed publisher
Pascual Guardia S, Ataya M, Ramírez Martínez I, Yelamos J, Chalela R, Bellido S, et al. Adaptive NKG2C+ natural killer cells are related to exacerbations and nutritional abnormalities in COPD patients. Respir Res. 2020;21:63 pubmed publisher
Pean P, Nouhin J, Ratana M, Madec Y, Borand L, Marcy O, et al. High Activation of γδ T Cells and the γδ2pos T-Cell Subset Is Associated With the Onset of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome, ANRS 12153 CAPRI NK. Front Immunol. 2019;10:2018 pubmed publisher
Campbell T, McSharry B, Steain M, Russell T, TSCHARKE D, Kennedy J, et al. Functional paralysis of human natural killer cells by alphaherpesviruses. PLoS Pathog. 2019;15:e1007784 pubmed publisher
Newhook N, Fudge N, Grant M. NK cells generate memory-type responses to human cytomegalovirus-infected fibroblasts. Eur J Immunol. 2017;47:1032-1039 pubmed publisher
Heath J, Newhook N, Comeau E, Gallant M, Fudge N, Grant M. NKG2C(+)CD57(+) Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8(+) T Cell Evolution towards Senescence. J Immunol Res. 2016;2016:7470124 pubmed publisher
Nielsen C, White M, Bottomley C, Lusa C, Rodríguez Galán A, Turner S, et al. Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals. J Immunol. 2015;194:4657-67 pubmed publisher
Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
Golden Mason L, McMahan R, Strong M, Reisdorph R, Mahaffey S, Palmer B, et al. Galectin-9 functionally impairs natural killer cells in humans and mice. J Virol. 2013;87:4835-45 pubmed publisher
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol. 2013;43:480-7 pubmed publisher
Böttger E, Multhoff G, Kun J, Esen M. Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70. PLoS ONE. 2012;7:e33774 pubmed publisher
Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, et al. Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Blood. 2008;111:3155-62 pubmed publisher
product information
master code :
FAB138A
SKU :
FAB138A-025
product name :
Human NKG2C/CD159c APC-conjugated Antibody
unit size :
25 Tests (also 100 Tests)
description :
The Human NKG2C/CD159c APC-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to NKG2C/CD159c/KLRC2. This antibody reacts with human. The Human NKG2C/CD159c APC-conjugated Antibody has been validated for the following applications: Flow Cytometry.
target :
NKG2C/CD159c
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
134591
conjugate :
Allophycocyanin
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.
gene symbol :
KLRC2
top caption :
Detection of NKG2C/CD159c antibody in Human PBMC lymphocytes antibody by Flow Cytometry.
applications :
Flow Cytometry
USD :
189 USD
alt names :
CD159 antigen-like family member C, CD159c, CD159c antigen, killer cell lectin-like receptor subfamily C, member 2, KLRC2, MGC138244, NK cell receptor C, NKG2-C, NKG2-C type II integral membrane protein, NKG2CNKG2-C-activating NK receptor
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.