product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human ULBP-1 PE-conjugated Antibody
catalog :
FAB1380P
quantity :
100 Tests
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
170818
reactivity :
human
application :
western blot, flow cytometry, FACS
more info or order :
citations: 26
Reference
Li Y, Zhou Y, Yu J, Kim Y, Li M, Lee D, et al. Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method. Nat Biotechnol. 2025;43:329-344 pubmed publisher
Lee S, Chae S, Jang I, Oh S, Kim S, Lee S, et al. B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies. EBioMedicine. 2024;110:105459 pubmed publisher
Jones A, Tuy K, Hawkins C, Quinn C, Saad J, Gary S, et al. Temozolomide and the PARP Inhibitor Niraparib Enhance Expression of Natural Killer Group 2D Ligand ULBP1 and Gamma-Delta T Cell Cytotoxicity in Glioblastoma. Cancers (Basel). 2024;16: pubmed publisher
Pascual Pasto G, McIntyre B, Hines M, Giudice A, Garcia Gerique L, Hoffmann J, et al. CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma. Nat Commun. 2024;15:7141 pubmed publisher
Fisher J, Doyle A, Graham L, Sonar S, Sale B, Henderson I, et al. XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression. Leukemia. 2023;37:2036-2049 pubmed publisher
Koh E, Lee H, Son W, Park G, Bae J, Park Y. Antitumor effects of NK cells expanded by activation pre‑processing of autologous feeder cells before irradiation in colorectal cancer. Oncol Lett. 2023;25:232 pubmed publisher
de Vries N, van de Haar J, Veninga V, Chalabi M, Ijsselsteijn M, van der Ploeg M, et al. γδ T cells are effectors of immunotherapy in cancers with HLA class I defects. Nature. 2023;613:743-750 pubmed publisher
Murayama Y, Kasahara Y, Kubo N, Shin C, Imamura M, Oike N, et al. NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma. Transl Oncol. 2022;25:101521 pubmed publisher
Wu H, Li K, Pan W, Guo M, Qiu D, He Y, et al. Venetoclax enhances NK cell killing sensitivity of AML cells through the NKG2D/NKG2DL activation pathway. Int Immunopharmacol. 2022;104:108497 pubmed publisher
Fan J, Shi J, Zhang Y, Liu J, An C, Zhu H, et al. NKG2D discriminates diverse ligands through selectively mechano-regulated ligand conformational changes. EMBO J. 2022;41:e107739 pubmed publisher
Seki T, Shimizu Y, Ishii K, Takahama Y, Kato K, Yano T. NK Cells Can Preferentially Target Prostate Cancer Stem-like Cells via the TRAIL/DR5 Signaling Pathway. Biomolecules. 2021;11: pubmed publisher
Fu R, Yu F, Wu W, Liu J, Li J, Guo F, et al. Bufalin enhances the killing efficacy of NK cells against hepatocellular carcinoma by inhibiting MICA shedding. Int Immunopharmacol. 2021;101:108195 pubmed publisher
Martínez Sánchez M, Fuster J, Campillo J, Galera A, Bermúdez Cortés M, Llinares M, et al. Expression of NK Cell Receptor Ligands on Leukemic Cells Is Associated with the Outcome of Childhood Acute Leukemia. Cancers (Basel). 2021;13: pubmed publisher
Liang Y, Tsai J, Cheng Y, Chan K, Hsu W, Lee C, et al. Chemotherapy agents stimulate dendritic cells against human colon cancer cells through upregulation of the transporter associated with antigen processing. Sci Rep. 2021;11:9080 pubmed publisher
Møller S, Mellergaard M, Madsen M, Bermejo A, Jepsen S, Hansen M, et al. Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells. Front Immunol. 2020;11:1968 pubmed publisher
Høgh R, Droujinine A, Møller S, Jepsen S, Mellergaard M, Andresen L, et al. Fumarate Upregulates Surface Expression of ULBP2/ULBP5 by Scavenging Glutathione Antioxidant Capacity. J Immunol. 2020;204:1746-1759 pubmed publisher
Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, et al. iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity. Stem Cell Reports. 2020;14:49-59 pubmed publisher
Chollat Namy M, Ben Safta Saadoun T, Haferssas D, Meurice G, Chouaib S, Thiery J. The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy. Cell Death Dis. 2019;10:695 pubmed publisher
Han Y, Xie W, Song D, Powell D. Control of triple-negative breast cancer using ex vivo self-enriched, costimulated NKG2D CAR T cells. J Hematol Oncol. 2018;11:92 pubmed publisher
Kamei R, Yoshimura K, Yoshino S, Inoue M, Asao T, Fuse M, et al. Expression levels of UL16 binding protein 1 and natural killer group 2 member D affect overall survival in patients with gastric cancer following gastrectomy. Oncol Lett. 2018;15:747-754 pubmed publisher
Pace M, Williams J, Kurioka A, Gerry A, Jakobsen B, Klenerman P, et al. Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function. PLoS Pathog. 2016;12:e1005782 pubmed publisher
Chitadze G, Lettau M, Luecke S, Wang T, Janssen O, Furst D, et al. NKG2D- and T-cell receptor-dependent lysis of malignant glioma cell lines by human ?? T cells: Modulation by temozolomide and A disintegrin and metalloproteases 10 and 17 inhibitors. Oncoimmunology. 2016;5:e1093276 pubmed
Vasu S, He S, Cheney C, Gopalakrishnan B, Mani R, Lozanski G, et al. Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts. Blood. 2016;127:2879-89 pubmed publisher
Parrish C, Scott G, Migneco G, Scott K, Steele L, Ilett E, et al. Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia. Leukemia. 2015;29:1799-810 pubmed publisher
Wang R, Sun P. Natural killer cell-mediated shedding of ULBP2. PLoS ONE. 2014;9:e91133 pubmed publisher
Jacobs S, Plessers J, Pinxteren J, Roobrouck V, Verfaillie C, Van Gool S. Mutual interaction between human multipotent adult progenitor cells and NK cells. Cell Transplant. 2014;23:1099-110 pubmed publisher
product information
master code :
FAB1380P
SKU :
FAB1380P
product name :
Human ULBP-1 PE-conjugated Antibody
unit size :
100 Tests
description :
The Human ULBP-1 PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to ULBP-1. This antibody reacts with human,xenograft. The Human ULBP-1 PE-conjugated Antibody has been validated for the following applications: Flow Cytometry,FACS,CAR-T (Flow Cytometry),Western Blot.
target :
ULBP-1
category :
Primary Antibodies
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
170818
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human ULBP-1
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Xenograft
specificity :
Stains human ULBP-1 cell transfectants. It does not stain cells transfected with ULBP-2 or ULBP-3.
gene symbol :
ULBP1
top caption :
Detection of ULBP-1 antibody in MOLT-4 Human Cell Line antibody by Flow Cytometry.
applications :
FACS,Flow Cytometry,CAR-T (Flow Cytometry),Western Blot
USD :
439 USD
alt names :
ALCAN-beta, MULT-1, N2DL1, N2DL-1, NKG2D ligand 1, NKG2DL, NKG2DL1, RAET1I, RAET1Ialcan-beta, Retinoic acid early transcript 1I, UL16 binding protein 1, UL16-binding protein 1, ULBP1
storage :
Store the unopened product at 2 - 8░ C. Do not use past expiration date. Protect from light.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.