This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human MICA PE-conjugated Antibody
catalog :
FAB1300P
quantity :
25 Tests (also 100 Tests)
price :
139 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
159227
reactivity :
human
application :
flow cytometry
citations: 9
Reference
López Cobo S, Pieper N, Campos Silva C, García Cuesta E, Reyburn H, Paschen A, et al. Impaired NK cell recognition of vemurafenib-treated melanoma cells is overcome by simultaneous application of histone deacetylase inhibitors. Oncoimmunology. 2018;7:e1392426 pubmed publisher
Fan X, Wang P, Zhang C, Zhang Y, Fu Y, Zhang C, et al. All-trans retinoic acid enhances cytotoxicity of CIK cells against human lung adenocarcinoma by upregulating MICA and IL-2 secretion. Sci Rep. 2017;7:16481 pubmed publisher
Niu C, Jin H, Li M, Zhu S, Zhou L, Jin F, et al. Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma. Oncotarget. 2017;8:5954-5964 pubmed publisher
Ke M, Wang H, Zhou Y, Li J, Liu Y, Zhang M, et al. SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice. Oncotarget. 2016;7:49509-49526 pubmed publisher
Gómez Lomelí P, Bravo Cuellar A, Hernández Flores G, Jave Suárez L, Aguilar Lemarroy A, Lerma Díaz J, et al. Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor. Cancer Cell Int. 2014;14:100 pubmed publisher
Robinet P, Baychelier F, Fontaine T, Picard C, Debre P, Vieillard V, et al. A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells. J Immunol. 2014;192:5332-42 pubmed publisher
Okita R, Mougiakakos D, Ando T, Mao Y, Sarhan D, Wennerberg E, et al. HER2/HER3 signaling regulates NK cell-mediated cytotoxicity via MHC class I chain-related molecule A and B expression in human breast cancer cell lines. J Immunol. 2012;188:2136-45 pubmed publisher
Lança T, Correia D, Moita C, Raquel H, Neves Costa A, Ferreira C, et al. The MHC class Ib protein ULBP1 is a nonredundant determinant of leukemia/lymphoma susceptibility to gammadelta T-cell cytotoxicity. Blood. 2010;115:2407-11 pubmed publisher
Dibra D, Cutrera J, Xia X, Birkenbach M, Li S. Expression of WSX1 in tumors sensitizes IL-27 signaling-independent natural killer cell surveillance. Cancer Res. 2009;69:5505-13 pubmed publisher
product information
brand :
R&D Systems
master code :
FAB1300P
SKU :
FAB1300P-025
product name :
Human MICA PE-conjugated Antibody
description :
The Human MICA PE-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to MICA. This antibody reacts with human. The Human MICA PE-conjugated Antibody has been validated for the following applications: Flow Cytometry, Knockout Validated.
target :
MICA
category :
Primary Antibodies
unit size :
25 Tests (also 100 Tests)
buffer :
Supplied in a saline solution containing BSA and Sodium Azide.
clonality :
Monoclonal
clone :
159227
conjugate :
Phycoerythrin
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human MICA
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human MICA in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant human MICB.
gene symbol :
MICA
catalog number base :
FAB1300P
applications :
Flow Cytometry, Knockout Validated
2020 USD :
139
2021 USD :
139 USD
alt names :
FLJ60820, MGC111087, PERB11.1
storage :
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.